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Researchers in the Netherlands have developed an incredibly accurate nanosensor which can detect metastatic cancer cells from just a single drop of blood in a major breakthrough for early detection and treatment of the disease.

PhD students Dilu Mathew from University of Twente and Pepijn Beekman from Wageningen University pooled their resources and developed a tiny system to detect tumor-derived extracellular vesicles (tdEVs), a particular type of cancer biomarker.

Their nanosensor is so sensitive it can detect cancer biomarkers on a broad spectrum of concentrations from 10 particles per microliter to 1 million particles per microliter, thanks to its incredibly small and delicate electrodes, shaped like two combs facing each other, with a gap of just 120 nanometers between them.

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A molecular switch has been identified by scientists at the University of California that controls the immune machinery which is responsible for chronic inflammation within the body; findings published in the journal Cell Metabolism may lead to new ways to halt and/or reverse age related conditions such as cancer, diabetes, Alzheimer’s and Parkinson’s disease.

“My lab is very interested in understanding the reversibility of aging,” said senior author Danica Chen, associate professor of metabolic biology, nutritional sciences and toxicology at UC Berkeley. “In the past, we showed that aged stem cells can be rejuvenated. Now, we are asking: to what extent can aging be reversed? And we are doing that by looking at physiological conditions, like inflammation and insulin resistance, that have been associated with aging-related degeneration and diseases.”

A bulky collection of NLRP3 inflammasome immune proteins which are responsible for sensing potential threats to the body and launching an inflammatory response were shown to be essentially switched off by removing some molecular matter in a deacetylation process. Overactivation of NLRP3 inflammasomes is linked to a range of chronic conditions such as cancer, dementia, diabetes, and multiple sclerosis; this study suggests that drugs targeted towards deacetylation these NLRP3 inflammasomes may help to prevent and/or treat many age related conditions and even possibly age related degeneration itself in general.

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Every crisis is an opportunity. With everyone staying home, this is the perfect opportunity for e-commerce, e-learning, online jobs, and big tech to expand. This is the beginning of a huge tech revolution. 2020 will be the techade (technology decade).

The virus is hitting China’s economy hard, but this is likely only temporary. China’s immune system is fighting back — building hospitals in record time, completely locking down a city and most importantly the entire nation uniting as one voice of support and solidarity.

Mario Cavolo called out the global response to the Coronavirus in his post “Something’s not right here folks” which originally went viral on LinkedIn and then subsequently all over Chinese social media. He compares the media response to Coronavirus with the H1N1 outbreak in the US, saying, “it’s not a conspiracy, it’s just a tragedy,” and “this vicious, political, xenophobic racist attacks and smearing of all things China needs to stop.”

What doesn’t break you only makes you stronger, and the Chinese people are resilient and will find ways to rise out of this crisis, likely coming back even stronger than before. How long that will take no-one yet knows, but the Chinese spirit is not even close to being broken, and we’ve seen how Chinese ingenuity in a time of crisis has led to entirely new operating models.

Continue reading “Could the Coronavirus make China Stronger than Ever? 10 Trends that Indicate it Will” | >