Lifeboat Foundation

“We have long known that oxidative stress and inflammation are involved in making arteries unhealthy over time, but we didn’t know why arteries begin to get inflamed and stressed. Something is triggering this,” Seals said. “We now suspect that, with age, the gut microbiota begins producing toxic molecules, including TMAO, which get into the blood stream, cause inflammation and oxidative stress and damage tissue.”

As our collection of resident gut bacteria changes with age, it increasingly produces harmful metabolites that damage veins and blood vessels, driving disease, a new study suggests.

A startup with alumni from MIT and Yale says it’s made a breakthrough in creating a next-generation material that should make it possible to 3D print literally anything out of thin air.

New York-based Mattershift has managed to create large-scale carbon nanotube (CNT) membranes that are able to combine and separate individual molecules.

“This technology gives us a level of control over the material world that we’ve never had before,” said Mattershift Founder and CEO Dr. Rob McGinnis in a release. “For example, right now we’re working to remove CO₂ from the air and turn it into fuels. This has already been done using conventional technology, but it’s been too expensive to be practical. Using our tech, I think we’ll be able to produce carbon-zero gasoline, diesel, and jet fuels that are cheaper than fossil fuels.”

Continue reading “A Real World ‘Star Trek’ Replicator Is Now Possible Thanks To New Breakthrough” »

The Onion is well known for biting satire. This is NOT The Onion.

Massimiliano Fedriga, a member of Italy’s far-right League party, is dead-set against the country’s mandatory vaccination laws. Guess who contracted chickenpox and had to spend four days in the hospital?

Instead, new research by McMaster behavioural scientists shows that in certain cases evolution works in the opposite direction, reversing individual improvements to benefit related members of the same group.

The research appears in the Journal of Evolutionary Biology, where lead author David Fisher shows that the increased evolution of selfless traits — such as sharing food and keeping watch for one another — is mathematically equivalent to the decreased evolution of individually beneficial traits.

“They’re two sides of the same coin,” Fisher explains. “On one side, traits evolve that benefit your kin, but don’t benefit you, because you’re helping your siblings or cousins. On the other side, traits that benefit you but cost your neighbours don’t evolve, because you’re causing damage to related individuals.”

I’ve posted or commented several times about relying on what I call single-study-science. The tendency to see some awesome scientific report and base one’s entire position on that one paper. This can be a problem in all areas of science.

A few months ago, PLOS ONE published a study of parental reports on gender dysphoria in adolescents and young adults, which was the subject of strong criticism and debate shortly after publication (see example here or here). We also received a large volume of personal communication, which I have personally reviewed. I would like to thank everyone who took the time to contact us with their assessment of this study.

“I have conducted numerous shipwreck projects around the world, many in depths greater than 4,000 and 5,000 meters,” Mearns says. “But I have never worked harder and had such fun as I did diving with our British and Omani team every day on this rewarding project.”

“You can only dream about finding such a rare and precious artifact as an astrolabe, but then to find such a historically important one in relatively good condition was a huge bonus.”

Templeton Prize Awarded To Marcelo Gleiser, Who Tackles ‘Mystery Of Who We Are The prestigious award comes with nearly $1.5 million in winnings. The physicist, who teaches at Dartmouth and has written for NPR, says he’s driven by the “many questions we still have no clue about.”

For the first time, one of the top prizes in mathematics has been given to a woman.

On Tuesday, the Norwegian Academy of Science and Letters announced it has awarded this year’s Abel Prize — an award modeled on the Nobel Prizes — to Karen Uhlenbeck, an emeritus professor at the University of Texas at Austin. The award cites “the fundamental impact of her work on analysis, geometry and mathematical physics.”

One of Dr. Uhlenbeck’s advances in essence described the complex shapes of soap films not in a bubble bath but in abstract, high-dimensional curved spaces. In later work, she helped put a rigorous mathematical underpinning to techniques widely used by physicists in quantum field theory to describe fundamental interactions between particles and forces.

Continue reading “Karen Uhlenbeck Is First Woman to Win Abel Prize for Mathematics” »

Last year, resTORbio announced the positive results of its phase 2b human trial, which targeted the aging immune system with an immune system-boosting drug. Now, the company has announced the news that its therapy is moving to a phase 3 study later this year after successful negotiation with the FDA.

Targeting the mTOR pathway of aging

ResTORbio is a biopharmaceutical company that is developing therapies that directly target the aging processes in order to prevent or cure age-related diseases. Its primary candidate drug is RTB101, which targets part of the mTOR pathway, one of the pathways involved in aging.