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Feb 21, 2020

Researchers wake monkeys

Posted by in categories: biotech/medical, neuroscience

A small amount of electricity delivered at a specific frequency to a particular point in the brain will snap a monkey out of even deep anesthesia, pointing to a circuit of brain activity key to consciousness and suggesting potential treatments for debilitating brain disorders.

Macaques put under with general anesthetic drugs commonly administered to human surgical patients, propofol and isoflurane, could be revived and alert within two or three seconds of applying low current, according to a study published today in the journal Neuron by a team led by University of Wisconsin–Madison brain researchers.

“For as long as you’re stimulating their brain, their behavior — full eye opening, reaching for objects in their vicinity, vital sign changes, bodily movements and facial movements — and their brain activity is that of a waking state,” says Yuri Saalmann, UW–Madison psychology and neuroscience professor. “Then, within a few seconds of switching off the stimulation, their eyes closed again. The animal is right back into an unconscious state.”

Feb 21, 2020

Submit a Grant Proposal

Posted by in category: life extension

The De Grey searching for researchers with work involving longevity… r.p.berry & AEWR.


Thank you for your interest in submitting a proposal for grant funding to SENS Research Foundation (SRF). Primarily, we fund projects by identifying research priorities through our Chief Science Officer’s (CSO) team and then either approaching parties with relevant expertise directly, or if appropriate generating requests for proposals (RFPs).

We do, however, also accept letters of intent for new grant proposals from interested parties for projects that fall specifically within our research mission. All such letters should clearly delineate the specific SENS target to which the proposal relates, and how the proposal would further progress toward developing therapies that remove, repair, replace, or render harmless that target.

All research projects are selected and periodically reviewed by our Research Development Committee (RDC), and its decisions are ratified by our Board of Directors. The RDC convenes twice yearly, at the end of the first and third calendar quarters.

Feb 21, 2020

Happy to announce Dr. Christian Schafmeister as a speaker for our 2020 Undoing Aging Conference

Posted by in categories: life extension, materials

Christian Schafmeister, Ph.D., Professor at Temple University in Philadelphia says: “We are developing “therapeutic catalysts” — small, robust, non-immunogentic catalysts that will permeate the tight spaces within tissues and fix things. Our specific targets include reversing the unwanted cross-links that develop in the extracellular matrix with aging.”

Enzymes, while possessing exquisite substrate-specificity, are limited by their molecular size in their ability to gain access to their substrate when it is embedded within dense material. We have always known that this may be a problem for our approach to restoring the elasticity of aged tissues. Christian’s fascinating work offers the potential to solve this issue with molecules that have the same catalytic function as enzymes but are much smaller and can therefore reach these embedded substrates.

Feb 21, 2020

NASA Eagleworks Space Warping and Quantum Vacuum Plasma Thruster

Posted by in categories: quantum physics, space travel

Popular Science discusses the Harold space warping project at NASA and Quantum Vacuum Plasma Thruster

Quantum Vacuum Plasma Thruster

White shows me into the facility and ushers me past its central feature, something he calls a quantum vacuum plasma thruster (QVPT). The device looks like a large red velvet doughnut with wires tightly wound around a core, and it’s one of two initiatives Eagleworks is pursuing, along with warp drive. It’s also secret. When I ask about it, White tells me he can’t disclose anything other than that the technology is further along than warp drive … Yet when I ask how it would create the negative energy necessary to warp space-time he becomes evasive.

Feb 21, 2020

Data for praying mantis mitochondrial genomes and phylogenetic constructions within Mantodea

Posted by in categories: biotech/medical, genetics

In this data article, we provide five datasets of mantis mitochondrial genomes: PCG123: nucleotide sequences of 13 protein-coding genes including all codon positions; PCG123R: nucleotide sequences of two rRNAs and 13 protein-coding genes including all codon positions; PCG12: nucleotide sequences of 13 protein-coding genes without third codon positions; PCG12R: nucleotide sequences of two rRNAs and 13 protein-coding genes without third codon positions, and PCGAA: amino acid sequences of 13 protein-coding genes. These were used to construct phylogenetic relationships within Mantodea and the phylogenetic trees inferred from Bayesian analysis using two data sets (PCG12R, PCGAA) and Maximum Likelihood analysis using four data sets (PCG123, PCG12, PCG12R and PCGAA). We also provide initiation codon, termination codon, amino acid length and nucleotide diversity (Pi) of protein-coding genes among 27 mantises. The whole mitochondrial genomes of 27 praying mantises were submitted to GenBank with the accession numbers KY689112 KY689138.

Feb 21, 2020

Solving a Higgs optimization problem with quantum annealing for machine learning

Posted by in categories: information science, particle physics, quantum physics, robotics/AI

A machine learning algorithm implemented on a quantum annealer—a D-Wave machine with 1,098 superconducting qubits—is used to identify Higgs-boson decays from background standard-model processes.

Feb 21, 2020

Quantum Physicists “Hold” Individual Atoms in Place for First Time

Posted by in categories: particle physics, quantum physics

Molecule Rules

The team even managed to observe two of three atoms collide to form a molecule — a process that has never been observed on this scale before. They were surprised at how long it took compared to previous experiments and calculations.

“By working at this molecular level, we now know more about how atoms collide and react with one another,” lead author and postdoc researcher Marvin Weyland said in a statement. “With development, this technique could provide a way to build and control single molecules of particular chemicals.”

Feb 21, 2020

Scientists Create a 5-atom Quantum Computer That Could Make Today’s Encryption Obsolete

Posted by in categories: computing, encryption, quantum physics

Circa 2016


MIT scientists have developed a 5-atom quantum computer, one that is able to render traditional encryption obsolete.

Feb 21, 2020

The Techno-Human Shell – A Jump in the Evolutionary Gap

Posted by in categories: bioengineering, biotech/medical, computing, cyborgs, nanotechnology

It is in this second phase when Darwinian evolutionary rivers will merge with the rivers of intelligent designers, represented by scientists, programmers and engineers, who will fuse organic natural biology, synthetic biology, and digital technology into a unified whole that future generations will deem their anatomy. The merger will serve to afford greater intelligence and, longer, healthier lives. In exchange, we will relinquish actual autonomy for apparent autonomy, where what was once considered “free will” will be supplanted by the deterministic logic of machinery somewhere in the mainstream of our unconscious.

Although in-the-body technology will have an explosive effect on commerce, entertainment, and employment, in the near term the concentration will be on medical devices, such as the innocuous pacemaker (essentially a working silicon-based computer, with sensors, memories, and a stimulation device with telecommunications to the outer world). In a second epoch, these devices will be gradually down-sized by advances in synthetic DNA, molecular- and nano-sized processors, each deployed alongside and within cells and organs as permanent non-organic, internal adjuncts to our anatomy for use as: nano-prosthetics, nano-stimulators/suppressors, artificial organ processors, metabolic and cognitive enhancers, and permanent diagnostic tools to ensure our physical and psychological well-being as we head toward a practically interminable lifetime.[6]

Continue reading “The Techno-Human Shell – A Jump in the Evolutionary Gap” »

Feb 21, 2020

Yuri Deigin on epigenetic rejuvenation, longevity research and transhumanists in politics

Posted by in categories: cryonics, genetics, life extension, transhumanism

Had a very frank discussion with Greg Mustreader about transhumanism, learned helplessness of society in the face of aging and death, insufficient sense of urgency among researchers of aging, epigenetic rejuvenation, cryonics, and so on. No filter! 😁.


My blog on Medium: https://medium.com/@mustreader

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