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Dec 16, 2019

New CRISPR-based system targets amplified antibiotic-resistant genes

Posted by in categories: bioengineering, biotech/medical, food, genetics, health

Taking advantage of powerful advances in CRISPR gene editing, scientists at the University of California San Diego have set their sights on one of society’s most formidable threats to human health.

A research team led by Andrés Valderrama at UC San Diego School of Medicine and Surashree Kulkarni of the Division of Biological Sciences has developed a new CRISPR-based gene-drive system that dramatically increases the efficiency of inactivating a gene rendering bacteria antibiotic-resistant. The new system leverages technology developed by UC San Diego biologists in insects and mammals that biases genetic inheritance of preferred traits called “active genetics.” The new “pro-active” genetic system, or Pro-AG, is detailed in a paper published December 16 in Nature Communications.

Widespread prescriptions of and use in animal food production have led to a rising prevalence of antimicrobial resistance in the environment. Evidence indicates that these environmental sources of antibiotic resistance are transmitted to humans and contribute to the current health crisis associated with the dramatic rise in drug-resistant microbes. Health experts predict that threats from antibiotic resistance could drastically increase in the coming decades, leading to some 10 million drug-resistant disease deaths per year by 2050 if left unchecked.

Dec 16, 2019

George Church on reversing aging | ApplySci @ Harvard

Posted by in categories: life extension, wearables

Recorded at ApplySci’s Wearable Tech + Digital Health + Neurotech conference — November 14, 2019 | Harvard Medical School.

Dec 16, 2019

Lofty promises for autonomous cars unfulfilled

Posted by in categories: robotics/AI, transportation

The first driverless cars were supposed to be deployed on the roads of American cities in 2019, but just a few days before the end of the year, the lofty promises of car manufacturers and Silicon Valley remain far from becoming reality.

Recent accidents, such as those involving Tesla cars equipped with Autopilot, a driver assistance software, have shown that “the technology is not ready,” said Dan Albert, critic and author of the book “Are We There Yet?” on the history of the American automobile.

He questioned the optimistic sales pitch that autonomous cars would help reduce road deaths — 40,000 every year in the United States, mostly due to human error — because these vehicles themselves have caused deaths.

Dec 15, 2019

Warning Issued For Millions Of Google Chrome Users

Posted by in category: futurism

The latest version of Google Chrome has a serious problem and it has already rolled out to millions…

Dec 15, 2019

Satellites Spot Earth’s Ocean Plastic From Orbit

Posted by in category: satellites

You can see plastic waste in our oceans from space 😳

Via NowThis

Dec 15, 2019

Why the Many-Worlds Interpretation of Quantum Mechanics Has Many Problems

Posted by in category: quantum physics

The idea that the universe splits into multiple realities with every measurement has become an increasingly popular proposed solution to the mysteries of quantum mechanics. But this “many-worlds interpretation” is incoherent, Philip Ball argues in this adapted excerpt from his new book Beyond Weird.

Dec 15, 2019

Briefing of the Longevity World Forum in Valencia, Spain (Nov 2019)

Posted by in category: life extension

Liz Parrish in Spanish is still good… AEWR.


Briefing of the highlights of second day (Nov 15, 2019) at the Longevity World Forum that took place in Valencia, Spain.

Continue reading “Briefing of the Longevity World Forum in Valencia, Spain (Nov 2019)” »

Dec 15, 2019

Join us on Thursday, December 19th at 7PM (our doors will open at 6 PM)!

Posted by in categories: cryonics, life extension, singularity

We will have a New Presentation on Age Reversal and Cryonics by Bill Faloon. 🤩 😎

Come early and enjoy snacks and conversation and stay afterward as we have a delicious 5-star dinner reception for Bill Faloon.

Before and after the service we will enjoy tasty food and interesting discussions on Age Reversal, Cryonics, Singularity and other topics of interest for all Immortalists.

Dec 15, 2019

Google’s AI Chief Wants to Do More With Less (Data)

Posted by in category: robotics/AI

Jeff Dean says the company is trying to build systems that have general smarts, rather than highly specialized intelligence.

Dec 15, 2019

Science Saturday: Mayo Clinic advances pain management beyond opioids

Posted by in categories: biotech/medical, health, science

The National Institutes of Health (NIH) estimates that in 2018, over 10 million teens and adults misused opioids. The prescription of opioids to treat patient pain is one of many factors contributing to this epidemic; to solve it, a multipronged approach is needed.

Two new Mayo Clinic studies — one in clinical practice and one in the laboratory — could offer new solutions to help patients manage pain without the use of opioids. These projects have been singled out for federal funding under the NIH’s Helping to End Addiction Long-Term (HEAL) Initiative, a multimillion dollar, multiorganizational approach to providing pain-treatment alternatives and turning the tide on the opioid crisis.

“Opioids remain one part of the continuum of pain treatment,” says Andrea Cheville, M.D., a rehabilitation physician at Mayo and member of the National Academy of Medicine. “There are other options that work as well, or better in some cases, with fewer risks. Our new research mirrors a broad Mayo priority — finding the safest, most effective way to help our patients manage acute or chronic pain.”