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The shocking case of Amanda Berry, 27, Gina DeJesus, 27, and Michele Knight, 32, all of whom were abducted as long as 11 years ago, provides fresh hope for parents still grappling with their own child’s disappearance.

Thousands of people go missing in the United States each year and many are never heard from again.

According to the National Center for Missing and Exploited Children, roughly 800,000 children are reported missing each year in the United States — that’s roughly 2,000 per day. Of those, there are 115 child “stranger abduction” cases each year, which means the child was taken by an unknown person.

It can be a gastrointestinal disease causing only diarrhea and abdominal pain. It can cause symptoms that may be confused with a cold or the flu. It can cause pinkeye, a runny nose, loss of taste and smell, muscle aches, fatigue, diarrhea, loss of appetite, nausea and vomiting, whole-body rashes, and areas of swelling and redness in just a few spots.

In a more severe disease, doctors have also reported people having heart rhythm problems, heart failure, kidney damage, confusion, headaches, seizures, Guillain-Barre syndrome, and fainting spells, along with new sugar control problems.

It’s not just a fever and coughing, leading to shortness of breath, like everyone thought at first.