It is now possible to use a cheap, lightweight and smartphone-powered DNA detector to identify DNA in blood, urine and other samples, on the spot.
At the moment, testing to identify DNA is done in laboratories using expensive, specialised equipment. To make this process faster and cheaper, Ming Chen at the Army Medical University in China and his colleagues developed a portable DNA detector made of 3D-printed parts that attach to a standard smartphone.
Now, scientists at Washington University in St. Louis have developed a way to use gene editing system CRISPR-Cas9 to edit a mutation in human-induced pluripotent stem cells (iPSCs) and then turn them into beta cells. When transplanted into mice, the cells reversed preexisting diabetes in a lasting way, according to results published in the journal Science Translational Medicine.
While the researchers used cells from patients with Wolfram syndrome—a rare childhood diabetes caused by mutations in the WFS1 gene—they argue that the combination of a gene therapy with stem cells could potentially treat other forms of diabetes as well.
Virtual Event
The Arecibo Observatory in Puerto Rico captured a radar image of 1998 OR2, which will zoom within 3.9 million miles (6.3 million kilometers) of our planet on April 29.
As electronic devices become progressively smaller, the technology that powers them needs to get smaller and thinner.
One of the key challenges scientists face in developing this technology is finding materials that can perform well at an ultrathin size. But now, Berkeley researchers think they may have the answer.
Led by Sayeef Salahuddin, professor of electrical engineering and computer sciences, and graduate student Suraj Cheema, a team of researchers has managed to grow onto silicon an ultrathin material that demonstrates a unique electrical property called ferroelectricity. The duo’s findings were published in the April 22 issue of Nature.
Circa 2010
An economical way to make sheets of the blingest material known to man could bring a new era of high-power electronics that don’t need cooling.
Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely. Using cells donated by patients with the disease, researchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center identified several small molecules that appear to reverse this cellular aging process. Suneet Agarwal, MD, Ph.D., the study’s senior investigator, hopes at least one of these compounds will advance toward clinical trials. Findings were published April 21 in the journal Cell Stem Cell.
If so, it could be the first treatment for dyskeratosis congenita, or DC, that could reverse all of the disease’s varying effects on the body. The current treatment, bone marrow transplant, is high-risk, and only helps restore the blood system, whereas DC affects multiple organs.
Engineering researchers developed a next-generation miniature lab device that uses magnetic nano-beads to isolate minute bacterial particles that cause diseases. Using this new technology improves how clinicians isolate drug-resistant strains of bacterial infections and difficult-to-detect micro-particles such as those making up Ebola and coronaviruses.
Ke Du and Blanca Lapizco-Encinas, both faculty-researchers in Rochester Institute of Technology’s Kate Gleason College of Engineering, worked with an international team to collaborate on the design of the new system — a microfluidic device, essentially a lab-on-a-chip.
Drug-resistant bacterial infections are causing hundreds of thousands of deaths around the world every year, and this number is continuously increasing. Based on a report from the United Nations, the deaths caused by antibiotics resistance could reach to 10 million annually by 2050, Du explained.
Tesla’s mobile app is one of the key parts of the Tesla ownership experience, and yet its security is lacking an important feature — two-factor authentication.
According to CEO Elon Musk, this will change in the near future.
When asked on Twitter whether there are any updates regarding two-factor authentication for the app, Musk said it’s “coming soon” (via Teslarati).
The collision of two black holes produced a gravitational wave signal unlike any other heard before.
Despite pushback from Hezbollah, the Lebanese parliament passed legislation Tuesday legalizing cannabis cultivation for medicinal and industrial purposes.