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Dec 1, 2024

PlayStation at 30: How Sony’s gray box conquered gaming

Posted by in category: entertainment

Japanese electronics giant Sony is set to celebrate 30 years since it launched the PlayStation console, the little gray box that catapulted the firm into the gaming big league.

PlayStation was Sony’s first foray into the world of video games and when it hit the shelves in Japan on December 3, 1994, the company needed to sell one million units to cover its costs.

In the end, the gadget became a legend, selling more than 102 million units, helping to launch many of the industry’s best-loved franchises and positioning Sony as a heavyweight in a hugely lucrative sector.

Dec 1, 2024

Texas lawmaker hopes new bill will create high-speed rail line from Dallas to Austin to San Antonio

Posted by in category: business

The proposed bill would connect the major business hubs while hopefully reducing crashes and traffic on I-35.

Dec 1, 2024

High-dose vitamin C: Promising treatment may extend survival of pancreatic cancer patients

Posted by in category: biotech/medical

A study published in the November issue of Redox Biology has found that adding intravenous, high-dose vitamin C to a chemotherapy regimen doubled the survival of patients with late-stage, metastatic pancreatic cancer from eight months to 16 months.

“This is a deadly disease with very poor outcomes for patients. The median survival is eight months with treatment, probably less without treatment, and the five-year survival is tiny. When we started the trial, we thought it would be a success if we got to 12 months survival, but we doubled overall survival to 16 months. The results were so strong in showing the benefit of this therapy for patient survival that we were able to stop the trial early,” explains Joseph J. Cullen, MD, FACS, a professor of Surgery and Radiation Oncology at the University of Iowa, in a statement to StudyFinds.

The study consisted of 34 patients with stage 4 pancreatic cancer who were randomized to two groups. One group received standard chemotherapy (gemcitabine and nab -paclitaxel). The other group received the same chemotherapy plus intravenous infusions of 75 grams of vitamin C three times a week.

Dec 1, 2024

New Human Species Extinct 200,000 Years Ago With Distinct Physical Traits Discovered

Posted by in category: evolution

A small group of ancient humans discovered in South Asia has the potential to change evolution as most people know it.

Dec 1, 2024

Dynamics of self-hybridized exciton–polaritons in 2D halide perovskites

Posted by in categories: solar power, sustainability

Basically I believe that this could be the answer for solar panels having super high output as exciton polariton energy is very powerful.


Self-hybridized exciton–polaritons are shown to enable sub-bandgap absorption and emission in 2D perovskites. The energy absorbed by the perovskites are also found to transfer to few-layer graphene in a heterostructure.

Dec 1, 2024

New Study Shows How Light Sleep Improves Your Cognition

Posted by in categories: biotech/medical, neuroscience

Although it is widely recognized that sleep boosts cognitive performance, the neural mechanisms underlying this effect—especially those associated with non-rapid eye movement (NREM) sleep—are still not well understood.

A new study by a team of researchers at Rice University and Houston Methodist’s Center for Neural Systems Restoration and Weill Cornell Medical College, coordinated by Rice’s Valentin Dragoi, has nonetheless uncovered a key mechanism by which sleep enhances neuronal and behavioral performance, potentially changing our fundamental understanding of how sleep boosts brainpower.

The research, published in Science, reveals how NREM sleep — the lighter sleep one experiences when taking a nap, for example — fosters brain synchronization and enhances information encoding, shedding new light on this sleep stage. The researchers replicated these effects through invasive stimulation, suggesting promising possibilities for future neuromodulation therapies in humans. The implications of this discovery potentially pave the way for innovative treatments for sleep disorders and even methods to enhance cognitive and behavioral performance.

Dec 1, 2024

Silicon chips are no longer sustainable. Here’s what’s next

Posted by in categories: computing, sustainability

The classic strategy of continually shrinking transistors in silicon chips to create faster, more powerful computers is starting to fail us.

“Even though silicon works at these extremely small dimensions, the energy efficiency required to do one calculation has been going up, and this makes it highly unsustainable,” Deep Jariwala, an engineering professor at the University of Pennsylvania, told the Wall Street Journal in 2022. “Energy-wise it doesn’t make sense anymore.”

Continue reading “Silicon chips are no longer sustainable. Here’s what’s next” »

Dec 1, 2024

Scientists Discover a Protein Key to Preventing Muscle Breakdown

Posted by in categories: genetics, health, nanotechnology

Chaperones are molecular machines that help proteins in the cell fold into their proper shape. Among them, UNC45 plays a critical role in muscle health by ensuring the proper function of myosin, a key protein essential for muscle movement. UNC45 manages this by directing damaged myosin to degradation pathways while guiding correctly folded myosin toward assembly. Researchers from Tim Clausen’s lab at the IMP have uncovered the mechanisms behind this process, providing new insights into how disruptions in myosin quality control can lead to serious muscle disorders. Their findings have been published in Nature Communications.

Muscle movement relies on the interaction between two key proteins: actin and myosin. These proteins slide past each other to generate the force needed for movement. For this process to work efficiently, actin and myosin must be precisely organized within the sarcomere, the basic structural and functional unit of muscle cells. This arrangement is crucial for maintaining muscle health, particularly during exercise, periods of stress, and as the body ages.

To ensure proteins achieve their correct shape, cells use specialized molecular assistants called chaperones. These chaperones act as caretakers, helping proteins fold and assemble correctly. For myosin, which makes up about 16% of the total protein in muscle cells, proper structure is especially important. One critical chaperone for this task is UNC45, found in all eukaryotic organisms. Identified through genetic studies, UNC45 plays a vital role in shaping myosin and preserving the integrity of the sarcomere. The importance of UNC45 is evident in severe muscle disorders, known as myopathies, which can result from mutations in the UNC45 gene.

Dec 1, 2024

That Healing Sound

Posted by in categories: biotech/medical, media & arts

When music is medicine.

Dec 1, 2024

ICI Meeting 2024 — Innovation in cardiovascular Intervention

Posted by in categories: innovation, robotics/AI

Discover how Artificial Intelligence is revolutionizing the field of cardiology, offering new perspectives and solutions that were once considered impossible.


The ICI Meeting 2024 is an acclaimed forum which aims to explore fuel, spark and be involved in the innovations that will shape the future of our cardiovascular systems.

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