Lifeboat Foundation

Researchers at MIT reported Thursday that they have harnessed artificial intelligence to identify a completely new antibiotic compound that killed all but one of the antibacterial-resistant pathogens they tested it on. Drug-resistant bacteria are a large and growing problem, causing 2.8 million infections and 35,000 deaths in the U.S. each year and more in developing countries, STAT News reports. The computer learning model developed at MIT, described in the journal Cell, has the potential to identify many new types of antibiotics.

The researchers named the compound halicin, after HAL, the initially useful, eventually murderous sentient computer in 2001: A Space Odyssey. They also discovered eight more promising antibacterial compounds, two of which appear very powerful. They tried out halicin on mice and plan to work with a nonprofit or drugmaker to see if it’s effective and safe in humans.

The MIT team’s machine-learning model independently looked for certain properties — in this case, the ability to kill E. coli and not harm humans — among about 2,500 molecules in a drug repurposing database. Halicin was originally considered as a treatment for diabetes.

Robots are replacing human manufacturing workers in France, and making companies more productive in the process.

Daron Acemoglu at the Massachusetts Institute of Technology and his colleagues analysed more than 55,000 French manufacturing firms, noting which ones bought robots between 2010 and 2015 and what impacts the purchases had.

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Researchers have discovered that the powerhouses of our cells, the mitochondria, also play a role in triggering cells to enter senescence, a dormant state in which cells cease to divide and begin to shut down, ready to die.

Mitochondria trigger cytoplasmic chromatin and inflammation

The new study shows that the mitochondria in each cell communicate with its nucleus, causing it to shut down and enter a senescent state [1]. Dr. Peter Adams, one of the study’s researchers, has spent over a decade investigating how chromatin clusters, a mixture of DNA and proteins typically encountered in the cell nucleus, actually leak out of the nucleus and into the cytoplasm in senescent cells. This leaking then triggers a cascade of inflammatory signals, which are linked to the onset of various age-related diseases.

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A new study suggests a better way to match patients with depression to a medication.

I get emotional talking about my lung cancer. When I was first diagnosed and learned how serious it was, I thought it was a death sentence. And it all started with something so small: a cyst under my armpit.

My husband and I usually go to all of our routine doctor’s visits together. At one of my husband’s appointments, I happened to mention the cyst, since it had been bothering me. I was hoping the doctor could help, but he said it was too big to take care of in the office, and made me an appointment with a surgeon.

At the time, the cyst removal didn’t seem like a big deal, and I didn’t think much of it. I was 72 years old, and I didn’t feel sick in any way. As part of the routine procedure prep, my surgeon ordered a chest X-ray. We were all surprised when the imaging showed that I had a cancerous tumor in my right lung that needed to be surgically removed. Initially, my surgeon told me it was Stage I, small, and not serious, so I wasn’t too concerned.

In some biology classes, teachers will place vials of spit into a funny looking contraption and let it spin around the samples until the stringy DNA separates from the rest of the saliva. It’s a pretty rudimentary experiment, but it quickly gets to the heart of not only your own genetic material, but also how centrifugal force works: Spinning really fast in a circle creates a force strong enough to push a moving object out and away from the center of its path.

But what happens when that moving object is a rocket that weighs thousands of pounds? We might find out as soon as this year, when a cryptic startup called SpinLaunch starts suborbital test flights of a rocket that is launched using an enormous centrifuge.

Here’s the gist: A centrifuge the size of a football field will spin a rocket around in circles for about an hour until its speed eventually exceeds 5,000 miles per hour. At that point, the rocket and its payload will feel forces 10,000 times stronger than gravity. When the centrifuge finally releases the rocket at launch speed, it should, practically speaking, fly through the stratosphere until it fires its engines at the periphery of our atmosphere.

“We are sidestepping all of the scientific challenges that have held fusion energy back for more than half a century,” says the director of an Australian company that claims its hydrogen-boron fusion technology is already working a billion times better than expected.

HB11 Energy is a spin-out company that originated at the University of New South Wales, and it announced today a swag of patents through Japan, China and the USA protecting its unique approach to fusion energy generation.

Fusion, of course, is the long-awaited clean, safe theoretical solution to humanity’s energy needs. It’s how the Sun itself makes the vast amounts of energy that have powered life on our planet up until now. Where nuclear fission – the splitting of atoms to release energy – has proven incredibly powerful but insanely destructive when things go wrong, fusion promises reliable, safe, low cost, green energy generation with no chance of radioactive meltdown.