Lifeboat Foundation

Is ageing a disease? One that can be ‘cured’? BBC’s Gabriela Torres meets the self-experimenters and scientists who are trying to dramatically extend our lives.

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A molecular switch has been identified by scientists at the University of California that controls the immune machinery which is responsible for chronic inflammation within the body; findings published in the journal Cell Metabolism may lead to new ways to halt and/or reverse age related conditions such as cancer, diabetes, Alzheimer’s and Parkinson’s disease.

“My lab is very interested in understanding the reversibility of aging,” said senior author Danica Chen, associate professor of metabolic biology, nutritional sciences and toxicology at UC Berkeley. “In the past, we showed that aged stem cells can be rejuvenated. Now, we are asking: to what extent can aging be reversed? And we are doing that by looking at physiological conditions, like inflammation and insulin resistance, that have been associated with aging-related degeneration and diseases.”

A bulky collection of NLRP3 inflammasome immune proteins which are responsible for sensing potential threats to the body and launching an inflammatory response were shown to be essentially switched off by removing some molecular matter in a deacetylation process. Overactivation of NLRP3 inflammasomes is linked to a range of chronic conditions such as cancer, dementia, diabetes, and multiple sclerosis; this study suggests that drugs targeted towards deacetylation these NLRP3 inflammasomes may help to prevent and/or treat many age related conditions and even possibly age related degeneration itself in general.

Autonomous delivery robots join the fight against the #coronavirus epidemic in Wuhan, China.

Every crisis is an opportunity. With everyone staying home, this is the perfect opportunity for e-commerce, e-learning, online jobs, and big tech to expand. This is the beginning of a huge tech revolution. 2020 will be the techade (technology decade).

The virus is hitting China’s economy hard, but this is likely only temporary. China’s immune system is fighting back — building hospitals in record time, completely locking down a city and most importantly the entire nation uniting as one voice of support and solidarity.

Mario Cavolo called out the global response to the Coronavirus in his post “Something’s not right here folks” which originally went viral on LinkedIn and then subsequently all over Chinese social media. He compares the media response to Coronavirus with the H1N1 outbreak in the US, saying, “it’s not a conspiracy, it’s just a tragedy,” and “this vicious, political, xenophobic racist attacks and smearing of all things China needs to stop.”

Continue reading “Could the Coronavirus make China Stronger than Ever? 10 Trends that Indicate it Will” »

Grocery and ecommerce shopping delivered… by drone? As shoppers get more delivered, companies look to cut last mile costs. Business Insider looks at how Amazon, UPS and Domino’s are experimenting with drone delivery.

New Zealand Police has recruited an unusual new officer to the force: an AI cop called Ella.

Ella is a life-like virtual assistant that uses real-time animation to emulate face-to-face interaction in an empathetic way.

Granule cells improve the storage capacity of the brain using the same trick that is used to compress digital audio files into an MP3.

Circa 2019

Nature breaks everything down—eventually. It’s time to accelerate the process, by engineering enzymes or microbes to chop plastic polymers into bits.