Multivalent interactions are crucial in transcriptional regulation. Here, by integrating specific multivalent molecules into dCas9-based activators, the authors provide valuable strategies to refine CRISPRa applications and achieve highly efficient gene transcription.
New technique lets robots detect force and interpret touch without extra sensors.
Researchers used internal sensors and machine learning to give robots an innate sense of touch, bypassing expensive external sensors.
The Dark Energy Camera has captured an image of the dazzling Coma Cluster, named after the hair of Queen Berenice II of Egypt. Not only significant in Greek mythology, this collection of galaxies was also fundamental to the discovery of the existence of dark matter.
Dark states are quantum states in which a system does not interact with external fields, such as light (i.e., photons) or electromagnetic fields. These states, which generally occur due to interferences between the pathways through which a system interacts with an external field, are undetectable using spectroscopic techniques.
Many quantum devices, from quantum sensors to quantum computers, use ions or charged atoms trapped with electric and magnetic fields as a hardware platform to process information.
The world’s largest and most powerful particle accelerator may be producing the world’s tiniest droplets of liquid, right under scientists’ noses. Researchers are digging into this subatomic enigma.
Integrated photonic circuits operating at room temperature combined with optical nonlinear effects could revolutionize both classical and quantum signal processing. Scientists from the Faculty of Physics at the University of Warsaw, in collaboration with other institutions from Poland as well as Italy, Iceland, and Australia, have demonstrated the creation of perovskite crystals with predefined shapes that can serve in nonlinear photonics as waveguides, couplers, splitters, and modulators.
An international team of scientists is the first to report incredibly small time delays in a molecule’s electron activity when the particles are exposed to X-rays.
Mathematicians at Loughborough University have turned their attention to a fascinating observation that has intrigued scientists and cocktail enthusiasts alike: the mysterious way ouzo, a popular anise-flavored liquor, turns cloudy when water is added.
Just a few years ago, researchers discovered that changing the angle between two layers of graphene, an atom-thick sheet of carbon, also changed the material’s electronic and optical properties. They then learned that a “twist” of 1.1 degrees—dubbed the “magic” angle—could transform this metallic material into an insulator or a superconductor, a finding that ignited excitement about a possible pathway to new quantum technologies.
