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DNA usually forms the classic double helix shape discovered in 1953—two strands wound around each other. Several other structures have been formed in test tubes, but this does not necessarily mean they form within living cells.

Quadruple helix structures, called DNA G-quadruplexes (G4s), have previously been detected in . However, the technique used required either killing the cells or using high concentrations of chemical probes to visualise G4 formation, so their actual presence within living cells under normal conditions has not been tracked, until now.

A research team from the University of Cambridge, Imperial College London and Leeds University have invented a fluorescent marker that is able to attach to G4s in living human cells, allowing them to see for the first time how the structure forms and what role it plays in cells.

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Imagine if this very cheap thing could treat coronavirus 🤔

That would put a wrench in profiteers plans:

Green coffee bean extract is a popular weight loss and health supplement, but does it work, and is it safe?

Green coffee beans, or raw coffee beans, are coffee beans that are not roasted. Green coffee bean extract is a popular weight loss supplement.

Some research also suggests that green coffee bean extract could have health benefits, such as improving blood pressure and cholesterol levels. This belief stems from the antioxidant properties and other pharmacologically active compounds in the unroasted beans.

Continue reading “Does green coffee bean extract work? A detailed review” | >

Samsung’s president and head of mobile communications T.M. Roh said in a blog post Monday that Samsung will announce five new products during the company’s big “Galaxy Unpacked” event on Aug. 5.

Samsung didn’t say what it will unveil, but it has teased a new Galaxy Note phone. The company typically unveils its large-screened Galaxy Note devices — best known for the pen that slides into the side — in August. Samsung usually packs in all of the latest hardware and software it has to offer into its Galaxy Note phones ahead of Apple’s iPhone event, which is typically held in September. Rumors suggest this year’s model will be called the Galaxy Note 20.

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The Sloan Digital Sky Survey (SDSS) released today a comprehensive analysis of the largest three-dimensional map of the universe ever created, filling in the most significant gaps in our possible exploration of its history.

“We know both the ancient history of the universe and its recent expansion history fairly well, but there’s a troublesome gap in the middle 11 billion years,” says cosmologist Kyle Dawson of the University of Utah, who leads the team announcing today’s results. “For five years, we have worked to fill in that gap, and we are using that information to provide some of the most substantial advances in cosmology in the last decade.”

The new results come from the extended Baryon Oscillation Spectroscopic Survey (eBOSS), an international collaboration of more than 100 astrophysicists that is one of the SDSS’s component surveys. At the heart of the new results are detailed measurements of more than two million galaxies and quasars covering 11 billion years of cosmic time.

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Circa 2016

One way of realizing controlled nuclear fusion reactions for the production of energy involves confining a hot plasma in a magnetic field. Here, the physics of magnetic-confinement fusion is reviewed, focusing on the tokamak and stellarator concepts.

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