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Three professors at the University of Southampton school of medicine have this week made a “major breakthrough” in the treatment of coronavirus patients and become paper millionaires at the same time.

Almost two decades ago professors Ratko Djukanovic, Stephen Holgate and Donna Davies discovered that people with asthma and chronic lung disease lacked a protein called interferon beta, which helps fight off the common cold. They worked out that patients’ defences against viral infection could be boosted if the missing protein were replaced.

The academics created a company, Synairgen, to turn their discoveries into treatments. It floated on the stock market in 2004, but a deal with AstraZeneca to treat viral infections in asthmatics fell through, and the shares collapsed.

Some users of Nest thermostats can no longer control the devices remotely, and the issue is forcing Google to replace the devices entirely if otherwise standard troubleshooting fails. The issue, which began popping up on Nest forums as early as last November and racking up more than 200 responses, is known as the “w5 error,” and it disables remote control of the company’s thermostats.

Controlling the temperature of your home with your smartphone when you’re out of the house or away from the physical device is pretty much the sole selling point of the Nest thermostat. So that makes this a pretty serious issue, even if you still can manually adjust the temperature on the device itself. Google says it’s aware of the problem and that it’s now offering replacements to owners of the device who cannot solve the issue through standard reset procedures.

“A very small number of Nest thermostat users are experiencing a known issue with the Wi-Fi chip that causes remote connectivity issues. This does not affect the thermostat’s ability to control the customer’s heating and cooling system in the home, but does impact the user’s ability to manage the thermostat remotely,” a Google spokesperson tells The Verge. “If a user sees this error and it can’t be resolved through troubleshooting, they are prompted to contact customer support for assistance and will be issued a replacement device.”

Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19).

The scientists propose that the antiviral and anti-inflammatory effects of activating nuclear factor erythroid 2-related factor 2 (Nrf2) may reduce symptoms and stop the “cytokine storm syndrome” that can be fatal in cases of COVID-19.

A pre-print version of the study can be accessed on the bioRxiv* server, while the manuscript undergoes peer review.