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Bioprinting could be used for testing potential treatments for Covid-19, cancer and other diseases.

Bioprinting’s importance for pharmaceutical analysis is paramount now, not only for potential Covid-19 treatments, but also for testing treatments for cancer and other diseases. Dr. Atala says that the organoids allow researchers to analyze a drug’s impact on an organ “without the noise” of an individual’s metabolism.

He cited Rezulin, a popular diabetes drug recalled in 2000 after there was evidence of liver failure. His lab tested an archived version of the drug, and Dr. Atala said that within two weeks, the liver toxicity became apparent. What accounts for the difference? An organoid replicates an organ in its purest form and offers data points that might not occur in clinical trials, he said, adding that the testing is additive to, rather than in lieu of, clinical trials.

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Interviewed by mika curtis, for the space renaissance academy mentorship programme.

We are honored and proud to publish this interview with Prof. Paul Ziolo, Psychohistorian, Senior Lecturer at the University of Liverpool, who kindly accepted to reply to some questions about his role as a Mentor of the Space Renaissance Academy. https://youtu.be/1UDJB7DS1Lo

The Space Renaissance Academy Mentorship Programme is a wide and very ambitious initiative. Our goal is to provide help to all students willing to have an active role in the incoming space settlement! We are realizing short video-recorded interviews to our Mentors: in 15 minutes, our anchorwomen are asking them about their interest for human expansion into space, their vision and how they think to motivate and inspire young generations to engage in space settlement. The SRI Volunteers team: Bharathi Sharma, Sachika Bhatia (Space Renaissance India), Corrinne Graham (Space Renaissance USA), Mika Curtis (Space Renaissance UK).

Here’s a presentation of the SR Academy Mentorship Programme. https://spacerenaissance.space/the-space-renaissance-acade…/

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A study published today (July 27, 2020) in The Lancet Digital Health by UPMC and University of Pittsburgh researchers demonstrates the highest accuracy to date in recognizing and characterizing prostate cancer using an artificial intelligence (AI) program.

“Humans are good at recognizing anomalies, but they have their own biases or past experience,” said senior author Rajiv Dhir, M.D., M.B.A., chief pathologist and vice chair of pathology at UPMC Shadyside and professor of biomedical informatics at Pitt. “Machines are detached from the whole story. There’s definitely an element of standardizing care.”

To train the AI to recognize prostate cancer, Dhir and his colleagues provided images from more than a million parts of stained tissue slides taken from patient biopsies. Each image was labeled by expert pathologists to teach the AI how to discriminate between healthy and abnormal tissue. The algorithm was then tested on a separate set of 1,600 slides taken from 100 consecutive patients seen at UPMC for suspected prostate cancer.

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A stunning flash of ultraviolet light from an exploding white dwarf has been detected by astronomers for only the second time, and could give researchers important clues about what spurs the demise of these ancient, spent stars.

Researchers became aware of this unusual supernova – called SN2019yvq – last December, only a day after the explosion took place. Within hours, scientists classified the event as a Type Ia supernova – not an unusual stellar event, ordinarily at least, except this time it was accompanied by the extremely rare flash of ultraviolet light.

“These are some of the most common explosions in the Universe,” says astrophysicist Adam Miller from Northwestern University.

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The self-eating process in embryonic stem cells known as chaperone-mediated autophagy (CMA) and a related metabolite may serve as promising new therapeutic targets to repair or regenerate damaged cells and organs, Penn Medicine researchers show in a new study published online in Science.

Human bodies contain over 200 different types of specialized cells. All of them can be derived from embryonic stem (ES) cells, which relentlessly self-renew while retaining the ability to differentiate into any cell type in adult animals, a state known as pluripotency. Researchers have known that the cells’ metabolism plays a role in this process; however, it wasn’t clear exactly how the cells’ internal wiring works to keep that state and ultimately decide stem cell fate.

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Goodbye gas stations.

During the second quarter earnings call, Elon Musk tentatively confirmed that Tesla would be making a compact car and a vehicle with high capacity. Granted, it would probably take a few more years before such vehicles are produced, but one thing seems certain. Considering Tesla’s speed and pace, it would not be surprising if Tesla’s compact car and high capacity EV causes the extinction of the internal combustion engine.

Tesla’s current lineup of vehicles, which comprise the Model S, Model 3, Model X, and Model Y, are great EVs, but they are still fairly large for their class. This includes the Model 3 and the Model Y, Tesla’s “smaller” vehicles in its lineup. This, together with the vehicles’ premium price, end up blocking the company from reaching its full potential in the auto market. With a compact car and a high capacity vehicle, however, things could drastically change for Tesla.

Compact and High Capacity EVs

Continue reading “Tesla’s next vehicles have the potential to usher in the extinction of gas cars” | >