Lifeboat Foundation

Networks are at the heart of everything from communications systems to pandemics. Now researchers have found that a unique type of network also underlies the structures of critical cellular compartments known as membraneless organelles. These findings may provide key insights into the role of these structures in both disease and cellular operations.

“Prior to this study, we knew the basic physical principle by which these protein-rich compartments form — they condense from the cytoplasm into liquid droplets like dew on a blade of grass,” said David Sanders, a post-doctoral researcher in Chemical and Biological Engineering at Princeton University. “But unlike dew drops, which are composed of a single component (water), cellular droplets are intimidatingly complex. Our work uncovers surprisingly simple principles that we think are universal to the assembly of liquid organelles, and opens new frontiers into studying their role in health and disease.”

Sanders is the lead author in an article in the journal Cell describing a blueprint for the assembly of these liquid structures, also called condensates. The researchers looked closely at two types of condensates, stress granules and processing bodies (“P-bodies”). In the Cell paper, researchers directed by Clifford Brangwynne, a professor of Chemical and Biological Engineering at Princeton and the Howard Hughes Medical Institute, combined genetic engineering and live cell microscopy approaches to reveal the rules underlying the assembly and structure of stress granules, and why they remain distinct from their close relatives, P-bodies.

Google plans to add a Zoom-like gallery view to its business- and education-focused Meet videoconferencing service and let users start calls and join meetings right from Gmail, Google’s GM and VP of G Suite Javier Soltero told Reuters in an interview. The additions come amid huge growth for Meet as families, students, and workers use the service while at home due to the COVID-19 pandemic.

The upcoming gallery view will let users display up to 16 meeting participants in one frame, according to Reuters. That functionality is coming later this month, said Soltero. Zoom’s gallery view, by contrast, lets you see the thumbnails of up to 49 people in one screen, if you have a powerful enough CPU to display them all.

State and federal governments are working on plans to “reopen” the country. But new models suggest that we will may not live normally for years.

A new study reviews the state of the art of aging biomarkers and explores the future development of even better ways of measuring biological age.

The need for better aging biomarkers

Human life expectancy has been increasing throughout the 20th and 21st centuries due to improvements such as better access to healthcare and sanitation, lower child mortality, reduction of poverty, and better education access.

Scientists at Tokyo Institute of Technology (Tokyo Tech) have generated low-cost extreme ultraviolet (EUV) light by creating tin thin-film spheres using a polymer electrolyte “soap bubble” as a template and irradiating it with a laser.

#EUV #photonics

The team from Tokyo Tech, working with colleagues from University College Dublin, set out to find efficient, scalable, low-cost laser targets that could be used to generate EUV. The scientists created a tin-coated microcapsule or “bubble” — a low-density structure weighing as little as 4.2 nanograms and with a high level of controllability. For the bubble, they used polymer electrolytes, which are a dissolution of salts in a polymer matrix. The salts act as surfactants to stabilize the bubble.

Continue reading “Nanosize Tin ‘Bubbles’ Could Provide Low-Cost Way to Generate EUV Light” »

LONDON (Reuters) — A million doses of a potential COVID-19 vaccine being developed by British scientists are already being manufactured and will be available by September, even before trials prove whether the shot is effective, the team said on Friday.

The Seattle woman was the first to receive this vaccine.

The new diagnostic tool, Detectr, shows promise in rapidly detecting COVID-19.

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