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Apr 13, 2020

Regeneron Granted Fundamental Patents Covering Mouse Antibody Technology Used in VelocImmune® Mice

Posted by in categories: biotech/medical, genetics

Circa 2013

These patents form part of Regeneron’s global patent portfolio, which together protect fundamental inventions behind Regeneron’s VelocImmune humanized mice. The two patents listed above specifically contain claims covering genetically modified mice that have unrearranged human immunoglobulin variable region gene segments at endogenous mouse immunoglobulin loci. The VelocImmune mice contain the full repertoire of human heavy chain immunoglobulin genes and kappa light chain genes, each linked to endogenous mouse constant regions. As a result, VelocImmune mice generate a normal and robust immune response which many believe is becoming the gold standard for making human antibody therapeutics. VelocImmune is also proving to be one of the most valuable technologies in biotechnology history, in terms of the licensing and collaboration revenues it has helped generate.


TARRYTOWN, N.Y., Aug. 7, 2013 /PRNewswire/ — Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the United States Patent and Trademark Office granted U.S. Patent No. 8,502,018 relating to methods of genetically modifying a mouse to make human antibodies. A similar European.

Apr 13, 2020

Big Brother Is Watching: 16 Unsettling Dystopian Books Like ‘1984’

Posted by in category: surveillance

Activity Post: Everyone is doing weird facebook activities, so I thought I would give it a try.

This is not a post for sharing anything but information in the comments section. Many like to read, and in a time of boredom reading passes time. I will start by posting a link to cool books to read, and in the comments section mention books you like to read or links of many books you like to read. Two books that changed my life were “Engines of Creation” by K Eric Drexler, and “The Society of Mind”, by Marvin Minsky…in fact name two books that have influenced you, and post a link with cool books to read, as that is more info…and we have no clue how long we will be locked up. Reading often leads to inspiration.


These 16 books like ‘1984’ include invasive rulers, rebels with a cause, and other dystopian themes. Like George Orwell’s novel, they remain with you long after the final page.

Apr 13, 2020

Interstellar object ‘Oumuamua believed to be ‘active asteroid’

Posted by in categories: asteroid/comet impacts, existential risks, space travel

The cigar-shaped interstellar visitor to our solar system known as ‘Oumuamua could be the remnants of a larger body that was torn apart by its host star, according to researchers.

The dark, reddish object that hurtled into our solar system in 2017 and was named after the Hawaiian word for messenger or scout has long puzzled scientists.

Among its peculiarities is the lack of an envelope of gas and dust that comets typically give off as they heat up. Further work by experts suggested the body was accelerated by the loss of water vapour and other gases – as seen with comets but not asteroids. The upshot was that ‘Oumuamua was labelled a “comet in disguise”.

Apr 13, 2020

Astronomers measure wind speed on a brown dwarf

Posted by in category: space

Astronomers have used the National Science Foundation’s Karl G. Jansky Very Large Array (VLA) and NASA’s Spitzer Space Telescope to make the first measurement of wind speed on a brown dwarf—an object intermediate in mass between a planet and a star.

Based on facts known about the giant planets Jupiter and Saturn in our own Solar System, a team of scientists led by Katelyn Allers of Bucknell University realized that they possibly could measure a brown dwarf’s speed by combining radio observations from the VLA and from Spitzer.

“When we realized this, we were surprised that no one else had already done it,” Allers said.

Apr 13, 2020

In Good News, Scientists Built a Device That Generates Electricity ‘Out of Thin Air’

Posted by in categories: biological, nanotechnology

They found it buried in the muddy shores of the Potomac River more than three decades ago: a strange “sediment organism” that could do things nobody had ever seen before in bacteria.

This unusual microbe, belonging to the Geobacter genus, was first noted for its ability to produce magnetite in the absence of oxygen, but with time scientists found it could make other things too, like bacterial nanowires that conduct electricity.

For years, researchers have been trying to figure out ways to usefully exploit that natural gift, and this year they might have hit pay-dirt with a device they’re calling the Air-gen. According to the team, their device can create electricity out of… well, almost nothing.

Apr 13, 2020

The Pope Just Endorsed Universal Basic Income

Posted by in category: economics

In an Easter letter to world leaders, Pope Francis opined that “this may be the time to consider a universal basic wage which would acknowledge and dignify the noble, essential tasks you carry out.”

“It would ensure and concretely achieve the ideal, at once so human and so Christian, of no worker without rights,” the Pope argued.

In the letter, Francis argued that many workers, including “street vendors, recyclers, carnies, small farmers, construction workers, dressmakers, the different kinds of caregivers” were being “excluded from the benefits of globalization,” while “the lockdowns are becoming unbearable.”

Apr 13, 2020

Reinforcement Learning a Self-driving Car AI in Unity

Posted by in categories: robotics/AI, transportation

Note: This article is for people who already have a basic idea about working with Unity and are interested in Neural Networks and Reinforcement Learning. No prior experience with neural networks and/or PhD required! This article provides all needed to obtain the following…

Apr 13, 2020

Team designs carbon nanostructure stronger than diamonds

Posted by in categories: engineering, nanotechnology

Researchers at the University of California, Irvine and other institutions have architecturally designed plate-nanolattices—nanometer-sized carbon structures—that are stronger than diamonds as a ratio of strength to density.

In a recent study in Nature Communications, the scientists report success in conceptualizing and fabricating the material, which consists of closely connected, closed-cell plates instead of the cylindrical trusses common in such structures over the past few decades.

“Previous beam-based designs, while of great interest, had not been so efficient in terms of mechanical properties,” said corresponding author Jens Bauer, a UCI researcher in mechanical & aerospace engineering. “This new class of plate-nanolattices that we’ve created is dramatically stronger and stiffer than the best beam-nanolattices.”

Apr 13, 2020

Closing in on ‘holy grail’ of room temperature quantum computing chips

Posted by in categories: computing, engineering, nanotechnology, quantum physics

To process information, photons must interact. However, these tiny packets of light want nothing to do with each other, each passing by without altering the other. Now, researchers at Stevens Institute of Technology have coaxed photons into interacting with one another with unprecedented efficiency — a key advance toward realizing long-awaited quantum optics technologies for computing, communication and remote sensing.

The team, led by Yuping Huang, an associate professor of physics and director of the Center for Quantum Science and Engineering, brings us closer to that goal with a nano-scale chip that facilitates photon interactions with much higher efficiency than any previous system. The new method, reported as a memorandum in the Sept. 18 issue of Optica, works at very low energy levels, suggesting that it could be optimized to work at the level of individual photons — the holy grail for room-temperature quantum computing and secure quantum communication.

“We’re pushing the boundaries of physics and optical engineering in order to bring quantum and all-optical signal processing closer to reality,” said Huang.

Apr 13, 2020

Clinical presentation and virological assessment of hospitalized cases of coronavirus disease 2019 in a travel-associated transmission cluster

Posted by in category: biotech/medical

Can you be reinfected with Covid-19?

I’m skeptical as to whether reinfection is possible or not from Covid-19. However studies have shown that the virus lasts longer than 2 weeks within the human body:

10 days: https://doi.org/10.1101/2020.03.05.

More than 2 weeks: https://jamanetwork.com/journals/jama/fullarticle/2762452

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