Lifeboat Foundation

This is very surreal. A study was done to assess the safety of common drugs, and COVID, and whether taking them leads to severe symptoms. There has been concern as these drugs increase ACE2 receptors coronavirus binds to. So someone had the bright idea of going through over 12,000 digital patients records to come up with the conclusion the drugs are safe to take and they do not cause worse symptoms. No animal studies, no clinical trials, and this was actually published.

“For the study, the researchers identified patients in the NYU Langone Health electronic health record with COVID-19 test results. For each identified patient with COVID-19 test results, the team discretely extracted medical history needed for the analysis, which compared treated and untreated patients.”

First you do a mouse study at least to review how coronavirus behaves in mice who are given the drugs, and compare it to mice not given the drugs. If science has been reduced to just going over records and coming to a conclusion, with no experimentation I have officially lost my mind.

Continue reading “Study finds high blood pressure medications safe for patients with COVID-19 disease” »

A cherry-red pickup truck in Carmel, Indiana runs on hydrogen without carrying any fuel cells. The engineer who developed this “hydrogen-on-tap” system hopes it can someday power cargo trucks and cruise ships worldwide.

The city of Carmel, Ind., has trucks for plowing snow, salting streets, and carrying landscaping equipment. But one cherry-red pickup can do something no other vehicle can: produce its own hydrogen.

A 45-kilogram metal box sits in the bed of the work truck. When a driver starts the engine, the device automatically begins concocting the colorless, odorless gas, which feeds into the engine’s intake manifold. This prevents the truck from guzzling gasoline until the hydrogen supply runs out. The pickup has no fuel cell module, a standard component in most hydrogen vehicles. No high-pressure storage tanks or refueling pumps are needed, either.

Continue reading “‘Hydrogen-On-Tap’ Device Turns Trucks Into Fuel-Efficient Vehicles” »

This robot contains the digitized brain of a worm, and without any outside input it just… works! Here’s what this could mean for the future of AI.

This Is How Your Brain Powers Your Thoughts — https://youtu.be/yxUkUaV2VPs

Continue reading “Scientists Put the Brain of a Worm Into a Robot… and It MOVED” »

Jukebox is a generative artificial intelligence model that can create music from raw audio. It’s probably a copyright nightmare.

To tackle this problem, researchers at the RIKEN Center for Biosystems Dynamics Research identified a gel that closely mimics the physicochemical properties of organs that have undergone the tissue clearing process. Starting with computer simulations and following up with laboratory tests, the team optimized the soaking solution temperature, dye and antibody concentrations, chemical additives, and electrical properties to produce the best staining and imaging results. They then tested their method with more than two dozen commonly used dyes and antibodies on mouse and marmoset brains.

Scans of an entire mouse brain and one hemisphere of a marmoset brain—rendered into 3D using light sheet microscopy—revealed the similarity between the two animals’ neural vascular systems, showing the use of the system for comparative anatomy, the researchers report this week in. They also showed that they could simultaneously stain and image up to four molecular targets in a mouse brain, a feat that “has never been reported before,” says Ludovico Silvestri, of the European Laboratory for Non-linear Spectroscopy, who was not involved in the research.

The team also used its technique to image an entire infant marmoset and a small human brain sample—something that could one day lead to new understandings of solid tumors and neurodegenerative diseases. The team says its approach to optimizing staining can be applied to other techniques to advance the entire field of 3D imaging.

Five of the world’s biggest central banks recently announced that they’ve banded together to seriously explore central bank digital currencies.

Boston biopharma startup resTORbio Inc. is revamping its pipeline to focus on cancer cell therapies through a reverse-merger.

Both studies were based on reviewing patients’ records, which does not provide evidence as strong as the results of controlled clinical trials, where patients are picked at random to take one treatment or another 🙄.

People taking widely used medicines did not face higher rates of infection or more severe illness, new research indicates.

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