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Replacing research animals with tools that better mimic human biology could improve medicine.

By Rachel Nuwer

When it came time for Itzy Morales Pantoja to start her Ph.D. in cellular and molecular medicine, she chose a laboratory that used stem cells—not only animals—for its research. Morales Pantoja had just spent two years studying multiple sclerosis in mouse models. As an undergraduate, she’d been responsible for ­giving the animals painful injections to induce the disease and then observing as they lost their ability to move. She did her best to treat the mice gently, but she knew they were ­suffering. “As soon as I got close to them, they’d start peeing—a sign of stress,” she says. “They knew what was coming.”

Researchers from Karolinska Institutet have shown that there is a connection between medication against ADHD and a reduced risk of dying prematurely.


Forskare från Karolinska Institutet har visat att det finns ett samband mellan medicinering mot adhd och minskad risk för att dö i förtid. Risken för dödsfall av onaturliga orsaker, som olyckor och överdoseringar, kan minska med en fjärdedel, enligt den nya studien publicerad i JAMA.

Alvaro Morales is the co-founder and CEO of Orb, a flexible usage-based billing engine for modern software pricing models.

Many SaaS companies want to leverage AI in their products. However, since AI is so new, pricing remains volatile. Costs can drop drastically for an AI model when the next iteration is out, and many companies lower their pricing in response to a competitor launch to gain or retain market share.

In addition to the fluctuating and unpredictable model prices, AI pricing is mostly based on usage. Customer usage is usually difficult to predict, which affects the costs your product will incur if it relies on AI models.

An international group of researchers has developed a novel approach that enhances the efficiency of the oxygen evolution reaction (OER), a key process in renewable energy technologies. By introducing rare earth single atoms into manganese oxide (MnO2), the group successfully modulated oxygen electronic states, leading to unprecedented improvements in OER performance.

A recent study led by University of Minnesota Twin Cities researchers provides fundamental insight into how light, electrons, and crystal vibrations interact in materials. The research has implications for developing on-chip architectures for quantum information processing, significantly reducing fabrication constraints, and thermal management.

Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have experimentally demonstrated that metasurfaces (two-dimensional materials structured at the nanoscale) can precisely control the optical properties of thermal radiation generated within the metasurface itself. This pioneering work, published in Nature Nanotechnology, paves the way for creating custom light sources with unprecedented capabilities, impacting a wide array of scientific and technological applications.