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A questionnaire developed by XPRIZE and Deep Longevity claims to be able to accurately predict your psychological age by using artificial intelligence (AI) to analyze your answers, which theoretically should fall close to your chronological age. The questionnaire is developed from a study published in Aging that used AI in an attempt to identify key hallmarks of psychological aging and the top risk factors that affect mortality.

While the questionnaire seems like a fun insight into whether you’re an old soul or a young gun at heart, there is an important scientific basis for an age-predicting AI. The newly developed technology represents the first AI aimed solely at using psychological aspects to predict age. The researchers hope it can contribute to understanding the role psychological clocks play in overall aging, as well as improving mental health and the feeling of youth.

“For the first time, AI can predict human psychological and subjective age and help identify the possible interventions that can be applied in order to help people feel and behave younger,” said Alex Zhavoronkov, PhD, founder and CLO of Deep Longevity and co-author of the study, in a statement.

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

The immune system fights bacteria, viruses and other pathogens by utilizing several types of T , all of which have receptors that are specific to particular antigens. On killer T cells, the receptor works in concert with three signaling modules and a coreceptor to destroy the . Michael Kuhns, Ph.D., an associate professor in the UArizona College of Medicine—Tucson Department of Immunobiology, copied the evolutionary design to engineer a five-module , or 5MCAR, T cell.

“The 5MCAR was an attempt to figure out if we could build something by biomimicry, using some of evolution’s natural pieces, and redirect T cells to do what we want them to do. We engineered a 5MCAR that would direct killer T cells to target autoimmune T cells that mediate Type 1 diabetes,” said Dr. Kuhns, who is member of the UArizona Cancer Center, BIO5 Institute and Arizona Center on Aging. “So now, a killer T cell will actually recognize another T cell. We flipped T cell-mediated immunity on its head.”

The crystalline solid BaTiS3 (barium titanium sulfide) is terrible at conducting heat, and it turns out that a wayward titanium atom that exists in two places at the same time is to blame.

The discovery, made by researchers from Caltech, USC, and the Department of Energy’s Oak Ridge National Laboratory (ORNL), was published on November 27 in the journal Nature Communications. It provides a fundamental atomic-level insight into an unusual thermal property that has been observed in several materials. The work is of particular interest to researchers who are exploring the potential use of crystalline solids with poor in thermoelectric applications, in which heat is directly converted into electric energy and vice versa.

“We have found that quantum mechanical effects can play a huge role in setting the thermal transport properties of materials even under familiar conditions like ,” says Austin Minnich, professor of mechanical engineering and applied physics at Caltech and co-corresponding author of the Nature Communications paper.

Researchers at Lancaster University have developed a new material that can store energy for months, and potentially years, at a time. The material can be activated by light, and then release the pent-up energy on demand in the form of heat.

The team started with a metal-organic framework (MOF), materials that are famous for being very porous and as such, having an extremely high surface area. That in turn allows them to hold onto large amounts of molecules, making them great for desalinating or filtering water, capturing carbon dioxide out of the air, or delivering drugs in the body.

For the new study, the Lancaster researchers tested out how well a MOF might be able to store energy. They started with a version of the material called a DMOF1, and loaded its pores with azobenzene molecules. This compound is excellent at absorbing light, which causes its molecules to physically change shape.

Future leather…may be made from fungus! Cool! 😃


Around five years ago, US companies MycoWorks and Ecovative invented and patented fungus-derived leather technologies. These technologies use the mushroom’s root-like structure, known as mycelium. When mycelium is grown on agricultural waste or sawdust, they produce a thick mat that can be treated to look like leather.

This natural biological process can be conducted anywhere since the roots are used and not the mushrooms. The process doesn’t need light; it turns waste into something useful and stores carbon by collecting it in the growing fungus.

Making fungi leather (or mycelium leather) is an overall significantly quicker process than traditional leather. It takes years to raise a cow to maturity, while going from a single spore to a finished fungi leather takes weeks.