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Socioeconomic Factors Associated With Migraine Medication Prescription at a Tertiary Headache CenterA Retrospective Cohort Analysis

Background and ObjectivesThe socioeconomic and demographic factors affecting the prescription of migraine medications are underexplored. Understanding these factors is critical to addressing health. We used our tertiary headache center’s prescription…

Northeastern discovery in quantum materials could make electronics 1,000 times faster

Researchers at Northeastern University have discovered how to change the electronic state of matter on demand, a breakthrough that could make electronics 1,000 times faster and more efficient.

By switching from insulating to conducting and vice versa, the discovery creates the potential to replace silicon components in electronics with exponentially smaller and faster quantum materials.

“Processors work in gigahertz right now,” said Alberto de la Torre, assistant professor of physics and lead author of the research. “The speed of change that this would enable would allow you to go to terahertz.”


Northeastern researchers discovered how to control quantum materials with light, potentially making electronics 1,000 times faster.

Additive Manufacturing Enables Advanced Thermal Control Systems for Next-Generation Space Missions

3D Systems is collaborating with researchers from Penn State University and Arizona State University on two projects sponsored by NASA intended to enable groundbreaking alternatives to current thermal management solutions.

Severe temperature fluctuations in space can damage sensitive spacecraft components, resulting in mission failure. By combining deep applications expertise with 3D Systems’ leading additive manufacturing solutions comprising Direct Metal Printing (DMP) technology and tailored materials and Oqton’s 3DXpert® software, the teams are engineering sophisticated thermal management solutions for the demands of next-generation satellites and space exploration.

The project led by researchers with Penn State University, Arizona State University, and the NASA Glenn Research Center in collaboration with 3D Systems’ Application Innovation Group (AIG) has resulted in processes to build embedded high-temperature passive heat pipes in heat rejection radiators that are additively manufactured in titanium. These heat pipe radiators are 50 percent lighter per area with increased operating temperatures compared with current state-of-the-art radiators, allowing them to radiate heat more efficiently for high-power systems.


By combining deep applications expertise with 3D Systems’ leading additive manufacturing solutions, research teams are engineering sophisticated thermal management solutions for the demands of next-generation satellites and space exploration.

Blood proteome regulation to control inflammation, age-associated organ dysfunction and mortality in sepsis

The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting for 90 percent of the total mass. Finding a protein that isn’t in this top 10 is a bit like looking for Waldo if only one rendition of the character remained in a collection of every “Where’s Waldo” comic ever produced.

This range of disparity in protein concentration is termed dynamic range, and it makes it more difficult for scientists to identify less-abundant proteins and their matching receptors.

Scientists published findings in Nature Communications demonstrating a strategy for identifying less-abundant proteins that bind with a specific type of receptor termed an endocytic lectin, and namely the mannose receptor Mrc1 (also known as CD206 and MMR). This approach enabled the research team to uncover hundreds of binding partners that together predicted Mrc1’s roles in our health.

Lipid nanoparticle stereochemistry shapes mRNA delivery safety and efficacy, study reveals

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs. Their findings, published in the Journal of the American Chemical Society, open the door to the development of safer and more effective vaccines and therapies.

To deliver therapeutic nucleic acids like mRNA into cells, scientists rely on (LNPs)—tiny, fat-based carriers that protect fragile genetic material, enabling it to survive in the body and reach target cells. A key component of these LNPs are ionizable lipids, which help mRNA enter cells and then release it effectively. One such lipid, ALC-315, was notably used in the Pfizer/BioNTech COVID-19 vaccine, a medical breakthrough that played a critical role in controlling the global pandemic.

Experimental Demonstration of Attoseconds-at-Harmonics at the SASE3 Undulator of the European XFEL

We report on observations of single spike spectra (3–13% of events) upon employing a previously proposed method for single spike generation via harmonic conversion. The method was tested at the soft X-ray SASE3 undulator of the European XFEL. The first part of the undulator allows one to amplify bunching at the fundamental as well as the higher harmonics. The downstream undulator is tuned to a harmonic, the fourth in our case, to amplify pulses with a shorter duration. We estimate the generated pulse duration within such a subset of short pulses at a level of 650 as. Considering the demonstrated probability of single spike events, this method is attractive for high repetition-rate free electron lasers.

AI Co-Processors, NPUs and The Future of Cutting-Edge Artificial Intelligence

This week’s Fish Fry is all about AI inference, NPUs and the Tensilica NeuroEdge 130 AI Co-Processor! My guest is Amol Borkar from Cadence Design Systems and we are chatting about the latest trends in AI inferencing, why there is a greater need now for AI co-processors than ever before and the multitude of benefits that the Tensilica NeuroEdge 130 AI Co-Processor can bring to your next design.

Scientists give robots a sense of touch with fabric that mimics human skin

Robots excel at many things, but having a good sense of touch is not among them. Whether dropping items or pinching them too tightly, which crushes the object, many robots struggle with these basic skills that humans have mastered.

Over the years, scientists have equipped robots with cameras and other tools that enable the machines to better sense objects. But a simple and cost-effective solution remains elusive.

A new electronic textile (E-textile), under development at the University at Buffalo, aims to address this problem. The technology, described in a study published July 30 in Nature Communications, mimics how nerves in our hands sense pressure and slipping while grasping objects.