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Scientists just cracked the code to editing entire chromosomes flawlessly

A group of Chinese scientists has created powerful new tools that allow them to edit large chunks of DNA with incredible accuracy—and without leaving any trace. Using a mix of advanced protein design, AI, and clever genetic tweaks, they’ve overcome major limitations in older gene editing methods. These tools can flip, remove, or insert massive pieces of genetic code in both plants and animals. To prove it works, they engineered rice that’s resistant to herbicides by flipping a huge section of its DNA—something that was nearly impossible before.

Vibration energy harvesting by ferrofluids in external magnetic fields

The development of wearable electronics and the current era of big data requires the sustainable power supply of numerous distributed sensors. In this paper, we designed and experimentally studied an energy harvester based on ferrofluid sloshing. The harvester contains a horizontally positioned cylindrical vial, half-filled with a ferrofluid exposed to a magnetic field. The vial is excited by a laboratory shaker and the induced voltage in a nearby coil is measured under increasing and decreasing shaking rates. Five ferrofluid samples are involved in the study, yielding the dependence of the electromotive force on the ferrofluid magnetization of saturation. The energy harvesting by ferrofluid sloshing is investigated in various magnetic field configurations. It is found that the most effective magnetic field configuration for the energy harvesting is characterized by the field intensity perpendicular to the axis of the vial motion and gravity. The harvested electric power linearly increases with the ferrofluid magnetization of saturation. The electromotive force generated by each ferrofluid is found identical for measurements in acceleration and deceleration mode. A significant reduction in the induced voltage is observed in a stronger magnetic field. The magneto-viscous effect and partial immobilization of the ferrofluid in the stronger magnetic field is considered. The magneto-viscous effect is documented by a supplementing experiment. The results extend knowledge on energy harvesting by ferrofluid sloshing and may pave the way to applications of ferrofluid energy harvesters for mechanical excitations with changing directions in regard to the magnetic field induction.

Rajnak, M., Kurimsky, J., Paulovicova, K. et al. Vibration energy harvesting by ferrofluids in external magnetic fields. Sci Rep 15, 26,701 (2025). https://doi.org/10.1038/s41598-025-12490-w.

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Pharmacy Professor Works to Unlock Secrets of Cellular Sugar

OXFORD, Miss. – A University of Mississippi pharmacy professor will study how sugar molecules on proteins could lead to new ways to detect and treat diseases using a prestigious grant from the National Science Foundation.

The NSF has awarded a Faculty Early Career Development Program grant to Jing Li, assistant professor of medical chemistry and research and assistant professor in the Research Institute of Pharmaceutical Science.

Li will use computer modeling to study the effects of sugar molecules connected to proteins. These molecules – known as glycosylation – affect ion channels that play a crucial role in brain activity, heartbeats and muscle movement.

Sea Cucumbers Could Hold Key to Stopping Cancer Spread

OXFORD, Miss. – Sea cucumbers are the ocean’s janitors, cleaning the seabed and recycling nutrients back into the water. But this humble marine invertebrate could also hold the key to stopping the spread of cancer.

A sugar compound found in sea cucumbers can effectively block Sulf-2, an enzyme that plays a major role in cancer growth, according to a University of Mississippi-led study published in Glycobiology.

“Marine life produces compounds with unique structures that are often rare or not found in terrestrial vertebrates,” said Marwa Farrag, a fourth-year doctoral candidate in the UM Department of BioMolecular Sciences.

“And so, the sugar compounds in sea cucumbers are unique. They aren’t commonly seen in other organisms. That’s why they’re worth studying.”

Farrag, a native of Assiut, Egypt, and the study’s lead author, worked with a team of researchers from Ole Miss and Georgetown University on the project.

Universal quantum computation using Ising anyons from a non-semisimple topological quantum field theory

Ising anyons are a promising platform for topological quantum computation, but braiding alone is not universal. Here, authors show that extending to non-semi simple TQFTs introduces new anyon types that enable universal quantum computation with Ising anyons.

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