Some mutations that disable SCN2A, one of the genes most strongly linked to autism, can unexpectedly make neurons hyperexcitable, a study in mice shows. The findings may help explain why a sizeable proportion of autistic children with mutations in SCN2A experience epileptic seizures.
Deleterious mutations in an autism-associated gene can make neurons hyperexcitable, raising the risk of epileptic seizures.
SENS founder Aubrey de Grey expects senescence-targeting sector will see Phase 3 trials within “a couple of years”.
Accelerating norway towards a low-carbon economy — bjørn kjærand haugland, co-founder and CEO, skift.
Bjørn Haugland is the co-founder and Chief Executive Officer of SKIFT Business Climate Leaders (https://www.skiftnorge.no/english), a Norwegian business-led climate initiative with a mission to accelerate the transition to a low-carbon economy and support the government in delivering on its national climate commitments by 2030. The coalition hopes to demonstrate, to businesses and the government, the business potential that exists in the low-carbon economy and help drive the transition.
Mr. Haugland is the former Executive Vice President and the Chief Sustainability Officer in DNV GL Group where he oversaw the groups sustainability performance and drove company-wide sustainability initiatives.
Mr. Haugland has extensive experience assisting multinational companies in areas such as corporate sustainability, innovation and business development. He was responsible for the Global Opportunity Report, a joint initiative together with UN Global Compact and Sustainia, a fact-based sustainability consulting and communication firm.
Mr. Haugland is today a board member at the University of Bergen, WWF, The Peace Research Institute Oslo (PRIO), Sporveien and Kezzler. He is also member of the advisory Board for Centre for Responsible Leadership. He is co-founder of Zeabuz, a new service for urban, emission free, autonomous ferries and Terravera, a tech foundation to make sustainability a reality by giving anyone insights to support their everyday decisions. He is member of the The Norwegian Board of Technology (NBT) that advises the Norwegian Parliament and Government on new technology as well as a member of Norwegian Academy of Technological Sciences.
International Health Management, Across 17 Countries, 60 Clinics, and 350 Staff — Dr. James Allen, Health Systems Thinkers, LLC.
Dr. James Allen is a primary care internal medicine specialist who developed a fascinating career in international health management and leadership.
Dr. Allen served in the U.S. public health service before moving to Indonesian Borneo in 1994. For the next 22 years he worked in community and occupational health across Asia, managing health teams in 14 countries. As Chevron’s Asia Pacific medical director, he led projects for TB control in Myanmar, primary care in the Philippines, Indonesia, Vietnam, and Bangladesh; and emergency medicine in Azerbaijan and rural China.
After moving to California headquarters in late 2015, Dr. Allen created a global strategy on corporate responsibility for health, establishing a data-based approach in alignment with the Institute for Health Metrics and Evaluation of Seattle. As Chevron’s senior consulting health scientist, he advised social investment teams in Australasia, Central Europe, Latin America, North America, and West Africa. Dr. Allen completed his career at Chevron in 2021 by leading the implementation of Covid-19 management practices for a consortium of oil and gas companies in Angola.
In 2012, Dr. Allen became an adjunct faculty member for the Levinson Institute’s Strategic Leadership for Healthcare Executives, previously affiliated with Harvard Medical School, and now with Pariveda Solutions and Rice University. His education includes a BA from Antioch College, MS from Rensselaer Polytechnic Institute, and his medical degree from Kirksville, MO. He is certified in internal medicine by the American Board of Internal Medicine, and has completed graduate studies in public health, occupational medicine, tropical medicine, toxicology, and healthcare finance and systems management from various institutions – Cornell, the Medical College of Wisconsin, NY Medical College and Singapore Management Institute.
The typical Australian will change careers five to seven times during their professional lifetime, by some estimates. And this is likely to increase as new technologies automate labor, production is moved abroad, and economic crises unfold.
Jobs disappearing is not a new phenomenon—have you seen an elevator operator recently? – but the pace of change is picking up, threatening to leave large numbers of workers unemployed and unemployable.
New technologies also create new jobs, but the skills they require do not always match the old jobs. Successfully moving between jobs requires making the most of your current skills and acquiring new ones, but these transitions can falter if the gap between old and new skills is too large.
LP 40–365 will probably leave the galaxy at some point, scientists say.
A strange metal-rich star is speeding through the Milky Way at almost 2 million mph (3 million kph). The cosmic shrapnel probably leave the galaxy at some point.
Some kinds of water pollution, such as algal blooms and plastics that foul rivers, lakes, and marine environments, lie in plain sight. But other contaminants are not so readily apparent, which makes their impact potentially more dangerous. Among these invisible substances is uranium. Leaching into water resources from mining operations, nuclear waste sites, or from natural subterranean deposits, the element can now be found flowing out of taps worldwide.
In the United States alone, “many areas are affected by uranium contamination, including the High Plains and Central Valley aquifers, which supply drinking water to 6 million people,” says Ahmed Sami Helal, a postdoc in the Department of Nuclear Science and Engineering. This contamination poses a near and present danger. “Even small concentrations are bad for human health,” says Ju Li, the Battelle Energy Alliance Professor of Nuclear Science and Engineering and professor of materials science and engineering.
Now, a team led by Li has devised a highly efficient method for removing uranium from drinking water. Applying an electric charge to graphene oxide foam, the researchers can capture uranium in solution, which precipitates out as a condensed solid crystal. The foam may be reused up to seven times without losing its electrochemical properties. “Within hours, our process can purify a large quantity of drinking water below the EPA limit for uranium,” says Li.
Posted in drones, food, military, surveillance
Drones are neat and fun and all that good stuff (I should probably add the caveat here that I’m obviously not referring to the big, terrible military variety), but when it comes to quadcopters, there’s always been the looming question of general usefulness. The consumer-facing variety are pretty much the exclusive realm of hobbyists and imaging.
We’ve seen a number of interesting applications for things like agricultural surveillance, real estate and the like, all of which are effectively extensions of that imaging capability. But a lot can be done with a camera and the right processing. One of the more interesting applications I’ve seen cropping up here and there is the warehouse drone — something perhaps a bit counterintuitive, as you likely (and understandably) associate drones with the outdoors.
Looking back, it seems we’ve actually had two separate warehouse drone companies compete in Disrupt Battlefield. There was IFM (Intelligent Flying Machines) in 2016 and Vtrus two years later. That’s really the tip of the iceberg for a big list of startups effectively pushing to bring drones to warehouses and factory floors.
A couple people from TRIM are in TRIM-X to see how it works a second time.
In this video Dr. Fahy discusses what we can do to make the most of our thymus without the growth hormone treatment, what the timing makes sense for rejuvenation of the thymus and whether the thymus is tied to the other hallmarks of aging.
Dr. Greg Fahy is a world renowned cryobiologist and is also the chief science officer, and co-founder, of Intervene Immune, a company which pioneers treatments for thymus regeneration and age-related immune system decline. Dr. Fahy Designed and led the pilot TRIIM trial which first time showing both thymus rejuvenation and reversal of human epigenetic age. He is now running the follow up phase II trial TRIIM-X with the aim of confirming and extending the results.
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Can we ever reverse-engineer our thinking? This is one of the questions addressed in my new cinematic documentary Consciousness: Evolution of the Mind making a splash around the world. The film is now available for viewing on demand on Vimeo, Plex, Tubi, Social Club TV and other global networks with its worldwide premiere aired on June 8, 2021. This is my take on the nature of consciousness and reverse engineering of our mental faculties in order to create AGI. Enjoy!
#Consciousness #Evolution #Mind #Documentary #Film #Introduction
A new documentary film Consciousness: Evolution of the Mind is now available for viewing on demand on Vimeo, Plex, Tubi, Social Club TV and other global networks with its worldwide premiere aired on June 8, 2021. This is a futurist’s take on the nature of consciousness and reverse engineering of our thinking. Hosted by the author of the book upon which the film is based ― The Syntellect Hypothesis: Five Paradigms of the Mind’s Evolution by Alex M. Vikoulov.
[Transcript} Hi! My name is Alex Vikoulov, I’m a futurist, evolutionary cyberneticist and philosopher of mind. In this film, you’re about to come across certain novel ideas and concepts that go beyond conventionality and some views of mainstream academia, so I urge you to keep an open mind! In this documentary I report my own findings and research along with certain logically consistent metaphysical extrapolations.
