Mayo Clinic proof-of-concept study shows that removal of senescent cells in the hippocampus of mice leads to improved cognitive responses.
Researchers at Tokyo Medical and Dental University (TMDU) in Japan show that melatonin and its metabolites promote the formation of long-term memories in mice and protect against cognitive decline.
Researchers at Tokyo Medical and Dental University (TMDU) showed that melatonin’s metabolite AMK can enhance the formation of long-term memories in mice. Memory of objects were tested after treatment with melatonin or two of its metabolites. Older mice that normally performed poorly on the memory task showed improvements as dosage increased. The metabolite AMK was found to be the most important as melatonin failed to improve memory if it was blocked from metabolizing into AMK.
Walk down the supplement aisle in your local drugstore and you’ll find fish oil, ginkgo, vitamin E, and ginseng, all touted as memory boosters that can help you avoid cognitive decline. You’ll also find melatonin, which is sold primarily in the United States as a sleep supplement. It now looks like melatonin marketers might have to do a rethink. In a new study, researchers led by Atsuhiko Hattori at Tokyo Medical and Dental University (TMDU) in Japan have shown that melatonin and two of its metabolites help memories stick around in the brain and can shield mice, and potentially people, from cognitive decline.
German drone technology startup Wingcopter has raised a $22 million Series A – its first significant venture capital raise after mostly bootstrapping. The company, which focuses on drone delivery, has come a long way since its founding in 2017, having developed, built and flown its Wingcopter 178 heavy-lift cargo delivery drone using its proprietary and patented tilt-rotor propellant mechanism, which combines all the benefits of vertical take-off and landing with the advantages of fixed-wing aircraft for longer-distance horizontal flight.
This new Series A round was led by Silicon Valley VC Xplorer Capital, as well as German growth fund Futury Regio Growth. Wingcopter CEO and founder Tom Plümmer explained in an interview that the addition of an SV-based investor is particularly important to the startup, since it’s in the process of preparing its entry into the U.S., with plans for an American facility, both for flight testing to satisfy FAA requirements for operational certification, as well as eventually for U.S.-based drone production.
Wingcopter has already been operating commercially in a few different markets globally, including in Vanuatu in partnership with Unicef for vaccine delivery to remote areas, in Tanzania for two-way medical supply delivery and in Ireland where it completed the world’s first delivery of insulin by drone beyond visual line of sight (BVLOS), the industry’s technical term for when a drone flies beyond the visual range of a human operator who has the ability to take control in case of emergencies.
Transport processes are ubiquitous in nature, but still raise many questions. The research team around Florian Meinert from the Fifth Institute of Physics at the University of Stuttgart has now developed a new method to observe a single charged particle on its path through a dense cloud of ultracold atoms. The results were published in Physical Review Letters and are further reported in a Viewpoint column in the journal Physics.
Meinert’s team used a Bose-Einstein condensate (BEC) for their experiments. This exotic state of matter consists of a dense cloud of ultracold atoms. By means of sophisticated laser excitation, the researchers created a single Rydberg atom within the gas. In this giant atom, the electron is a thousand times further away from the nucleus than in the ground state and thus only very weakly bound to the core. With a specially designed sequence of electric field pulses, the researchers snatched the electron away from the atom. The formerly neutral atom turned into a positively charged ion that remained nearly at rest despite the process of detaching the electron.
In the next step, the researchers used precise electric fields to pull the ion in a controlled way through the dense cloud of atoms in the BEC. The ion picked up speed in the electric field, collided on its way with other atoms, slowed down and was accelerated again by the electric field. The interplay between acceleration and deceleration by collisions led to a constant motion of the ion through the BEC.
The latest Starlink satellites launched on Jan. 24 are equipped with laser links, and all Starlink satellites launched next year will be equipped with laser inter-satellite links, Elon Musk, SpaceX chief engineer confirmed on Twitter.
“All sats launched next year will have laser links. Only our polar sats have lasers this year and are v [version] 0.9,” Musk tweeted on Monday.
A Twitter user noticed a difference in a photo of the stack of 10 Starlink satellites deployed on Sunday’s Transporter-1 rideshare mission, and asked Musk if an object that looked like a black pipe was lasers, which he confirmed.
Laser beams can be used to change the properties of materials in an extremely precise way. This principle is already widely used in technologies such as rewritable DVDs. However, the underlying processes generally take place at such unimaginably fast speeds and at such a small scale that they have so far eluded direct observation. Researchers at the University of Göttingen and the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen have now managed to film, for the first time, the laser transformation of a crystal structure with nanometre resolution and in slow motion in an electron microscope. The results have been published in the journal Science.
The team, which includes Thomas Danz and Professor Claus Ropers, took advantage of an unusual property of a material made up of atomically thin layers of sulfur and tantalum atoms. At room temperature, its crystal structure is distorted into tiny wavelike structures—a “charge-density wave” is formed. At higher temperatures, a phase transition occurs in which the original microscopic waves suddenly disappear. The electrical conductivity also changes drastically, an interesting effect for nano-electronics.
In their experiments, the researchers induced this phase transition with short laser pulses and recorded a film of the charge-density wave reaction. “What we observe is the rapid formation and growth of tiny regions where the material was switched to the next phase,” explains first author Thomas Danz from Göttingen University. “The ultrafast transmission electron microscope developed in Göttingen offers the highest time resolution for such imaging in the world today.” The special feature of the experiment lies in a newly developed imaging technique, which is particularly sensitive to the specific changes observed in this phase transition. The Göttingen physicists use it to take images that are composed exclusively of electrons that have been scattered by the crystal’s waviness.
Puts into perspective the cycles and forces that have driven the successes and failures of all the world’s major countries throughout history. Dalio reveals the timeless and universal dynamics that were behind these shifts, while also offering practical principles for policymakers, business leaders, investors, and others operating in this environment.
From the #1 New York Times bestselling author of Principles and legendary investor Ray Dalio, who has spent half a century studying global markets, The Changing World Order examines history’s most turbulent economic and political periods to reveal why the times ahead will likely be radically different from those we’ve experienced in our lifetimes.
‘The Death of Death’ — David Wood and Jose Cordeiro.
“La mort de la mort — les avancées scientifiques vers l’immortalité” was published on 21st January 2021 and is available in bookshops throughout France, Belgium, Luxembourg, and Switzerland, as well as online — see e.g. https://www.amazon.fr/mort-avanc%C3%A9es-scientifiques-vers-…875422200/
Continue reading “Introducing La Mort de la Mort — English” »
If our universe is a bubble that inflated inside a larger multiverse, it might bear scars from collisions with nearby bubbles.
What lies beyond all we can see? The question may seem unanswerable. Nevertheless, some cosmologists have a response: Our universe is a swelling bubble. Outside it, more bubble universes exist, all immersed in an eternally expanding and energized sea — the multiverse.
The idea is polarizing. Some physicists embrace the multiverse to explain why our bubble looks so special (only certain bubbles can host life), while others reject the theory for making no testable predictions (since it predicts all conceivable universes). But some researchers expect that they just haven’t been clever enough to work out the precise consequences of the theory yet.
