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Sun, Sep 12 at 12 PM PDT.

This is an invitation to the Annual General Meeting of the Cryonics Institute & the Immortalist Society.

The Cryonics Institute, Annual General Meeting (AGM) will be held at 3:00pm to 6:30pm on Sunday, September 12th, 2021 at the Infinity Hall 16650 E. 14 Mile Rd, Fraser, MI 48026 (USA) for more information visit www.infinityhallsidebar.com or call 586−879−6157. Tours at the CI facility will be from 1:00pm to 2:30pm 24355 Sorrentino Court, Clinton Township, (Michigan) 48035 (USA).

The AGM of the Immortalist Society will be held after the CI AGM on the same day at the same location. The two meetings generally last most of the afternoon. A buffet dinner & social follow. The CI facility will be open to guests and visitors two hours before the meeting begins.

Continue reading “CI Annual General Meeting 2021” | >

Not sure how interesting this will be to people who know a lot on aging/longevity research.

A team of researchers at Brigham and Women’s Hospital and Harvard Medical School have found evidence of mouse and human germline cells resetting their biological age. In their paper published in the journal Science Advances, the group describes their study of the aging process in germline cells and what they found by doing so.

As animals grow older, all of the cells in their body replicate themselves repeatedly. As the process continues, errors in replicating and other external factors (such as exposure to pollutants) lead to gradual decay in cell quality, which is all part of the natural aging process. In this new effort, the researchers have found evidence showing that have a mechanism for resetting this process, allowing offspring to reset their aging clocks.

Germline cells pass on from parent to offspring during the reproductive process. For many years, scientists have wondered why these cells do not inherit the age of their parents. And for many years, they assumed that the cells were ageless, but recent work has shown that they do, in fact, age. So that raised the question of how offspring are able to begin their lives with fresh cells.

Continue reading “Mouse and human germline cells appear to reset their biological age” | >

The human body contains hundreds of different types of cells, with stem cells working like blank canvases that can be adapted and reproduced to help our tissues grow and repair themselves. However, once hijacked, the same kind of cell proliferation can be damaging, as happens in cancer tumors.

Scientists have now discovered a new resting phase for neuroepithelial cells — the stem cells of the central nervous system — which appears to put them in a kind of dormancy. If we can work out how to apply this to cancer cells too, we could get to the stage of being able to put brain tumors to ‘sleep’.

“The primary feature of any cancer is that the cells are proliferating,” says biomedical engineer Christopher Plaisier, from Arizona State University. “If we could get in there and figure out what the mechanisms are, that might be a place to slow them down.”

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Experts are excited by the concept of microreactors because nuclear facilities have historically relied on economies of scale — a paradigm this tech could reverse.

“Microreactors promise to turn this paradigm on its head by approaching cost competitiveness through technological learning,” Alex Gilbert from the nuclear power think tank Nuclear Innovation Alliance, told CNBC.

Oklo’s “fast reactor” plant uses energy from already-spent nuclear reactor fuel, technology that has been around since the 1950s, according to CNBC.

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Walmart will offer a less expensive private label version of analog insulin for diabetes patients who struggle to afford their medication, the retail and pharmacy giant said June 29.

Novo Nordisk will manufacture the insulin, called ReliOn NovoLog. Walmart said it will become available at Walmart pharmacies the week of June 27 and at Sam’s Club pharmacies in mid-July.

A vial of ReliOn NovoLog will cost $72.88, and a package of prefilled pens will cost $85.88. Walmart said these products will save patients between 58 and 75 percent of the price of other insulin products on the market.

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Papers referenced in the video:

Loss of Life Expectancy by 10 Years or More From Elevated Aspartate Aminotransferase: Finding Aspartate Aminotransferase a Better Mortality Predictor for All-Cause and Liver-Related than Alanine Aminotransferase.
https://pubmed.ncbi.nlm.nih.gov/31425154/

Implication of liver enzymes on incident cardiovascular diseases and mortality: A nationwide population-based cohort study.
https://pubmed.ncbi.nlm.nih.gov/29491346/

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The ability to precisely control the various properties of laser light is critical to much of the technology that we use today, from commercial virtual reality (VR) headsets to microscopic imaging for biomedical research. Many of today’s laser systems rely on separate, rotating components to control the wavelength, shape and power of a laser beam, making these devices bulky and difficult to maintain.

Now, researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences have developed a single that can effectively tune the different properties of light, including wavelength, without the need of additional optical components. The metasurface can split light into multiple beams and control their shape and intensity in an independent, precise and power-efficient way.

The research opens the door for lightweight and efficient optical systems for a range of applications, from quantum sensing to VR/AR headsets.

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