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The Conboys are looking at human trials soon but not with E5. it will be interesting to see how their trial compares to this E5 dog trial.

In this video Dr. Fahy shares his opinion on some of the up and coming anti-aging therapies, including NAD boosters, Hyperbaric Oxygen Chambers and senolytics.

Intervene Immune website:

Intro page


Contact to join the trial or invest.

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Dr. Greg Fahy is a world renowned cryobiologist and is also the chief science officer, and co-founder, of Intervene Immune, a company which pioneers treatments for thymus regeneration and age-related immune system decline. Dr. Fahy Designed and led the pilot TRIIM trial which first time showing both thymus rejuvenation and reversal of human epigenetic age. He is now running the follow up phase II trial TRIIM-X with the aim of confirming and extending the results.

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Continue reading “E5 On Dogs Project: Validating The 54% Reduction In Epigenetic Age | Dr Greg Fahy Episode 8” | >

Quick – define common sense

Despite being both universal and essential to how humans understand the world around them and learn, common sense has defied a single precise definition. G. K. Chesterton, an English philosopher and theologian, famously wrote at the turn of the 20th century that “common sense is a wild thing, savage, and beyond rules.” Modern definitions today agree that, at minimum, it is a natural, rather than formally taught, human ability that allows people to navigate daily life.

Common sense is unusually broad and includes not only social abilities, like managing expectations and reasoning about other people’s emotions, but also a naive sense of physics, such as knowing that a heavy rock cannot be safely placed on a flimsy plastic table. Naive, because people know such things despite not consciously working through physics equations.

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What is causing chronic inflammation?

Summary: A new study adds to the growing body of research linking inflammation to depression. Researchers found the molecule histamine directly inhibits the release of serotonin in the brain by attaching to inhibitory receptors on serotonin neurons in mice.

Source: Imperial College London

The findings, from researchers at Imperial College London and University of South Carolina, add to mounting evidence that inflammation, and the accompanying release of the molecule histamine, affects a key molecule responsible for mood in the brain – serotonin.

If replicated in humans, the findings – which identify histamine as a ‘new molecule of interest’ in depression – could open new avenues for treating depression, which is the most common mental health problem worldwide.

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The gut microbiota plays an important role in human health and the prevention of disease. As a result, changes in its regular functioning may play a part in some medical conditions, such as irritable bowel syndromeTrusted Source, obesityTrusted Source, and cardiovascular diseasesTrusted Source.

A recent study investigates the connection between high fat diets, gut bacteria, and an increased risk of developing heart disease.

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New evidence shows that patients with Long COVID syndrome continue to have higher measures of blood clotting, which may help explain their persistent symptoms, such as reduced physical fitness and fatigue.

The study, led by researchers from RCSI University of Medicine and Health Sciences, is published in the Journal of Thrombosis and Haemostasis.

Previous work by the same group studied the dangerous clotting observed in patients with severe acute COVID-19. However, far less is known about Long COVID syndrome, where symptoms can last weeks to months after the initial infection has resolved and is estimated to affect millions of people worldwide.

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An artificial neural network (AI) designed by an international team involving UCL can translate raw data from brain activity, paving the way for new discoveries and a closer integration between technology and the brain.

The new method could accelerate discoveries of how brain activities relate to behaviors.

The study published today in eLife, co-led by the Kavli Institute for Systems Neuroscience in Trondheim and the Max Planck Institute for Human Cognitive and Brain Sciences Leipzig and funded by Wellcome and the European Research Council, shows that a , a specific type of deep learning , is able to decode many different behaviors and stimuli from a wide variety of brain regions in different species, including humans.

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In the study, researchers in the laboratory of Anna Penn, MD, Ph.D., now at Columbia University Vagelos College of Physicians and Surgeons and previously at Children’s National Hospital in Washington, D.C., found that reducing amounts of a single hormone, called allopregnanolone (ALLO), in the placenta caused brain and behavior changes in male offspring that resemble changes seen in some people with autism spectrum disorder. The study also found that both brain structure and behavioral changes in the mice could be prevented with a single injection of ALLO in late pregnancy.

Preterm birth has been shown to increase the risk of autism spectrum disorders and other developmental problems, particularly in males. The more premature a baby is, the greater the risk of either motor or cognitive deficits. What does the preterm baby lose that is so critical to long-term outcomes?

A new study, in mice, suggests that one factor may be the loss of a placental hormone that the developing would normally see in the second half of pregnancy.

The study is the first to provide direct evidence that loss of a placental hormone alters long-term brain development.

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