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Nuclear Pore Complexes and Genome Integrity — Dr. Veronica Rodriguez-Bravo Ph.D., Sidney Kimmel Cancer Center — Jefferson Health, Thomas Jefferson University.


Dr. Veronica Rodriguez-Bravo, PhD, is Assistant Professor, Department of Cancer Biology, at the Sidney Kimmel Cancer Center, Thomas Jefferson University, in Philadelphia, PA, USA. (https://sidneykimmelcancercenter.jeffersonhealth.org/)

Dr. Rodriguez-Bravo obtained her PhD in Pathology and Cell Biology (Summa Cum Laude) from the University of Barcelona in 2007, where she also received the Extraordinary Doctorate Award for her studies on the distinct DNA replication checkpoint mechanisms of tumor cells. During her postdoctoral training at the Experimental Oncology Department of the University Medical Center of Utrecht (UMC, The Netherlands) and at the Molecular and Cell Biology Programs of Memorial Sloan Kettering Cancer Center (MSKCC, New York), she specialized in the study of chromosome segregation during mitosis and the role of nuclear pores in genome integrity maintenance.

Quantum computing is coming on leaps and bounds. Now there’s an operating system available on a chip thanks to a Cambridge University-led consortia with a vision is make quantum computers as transparent and well known as RaspberryPi.

This “sensational breakthrough” is likened by the Cambridge Independent Press to the moment during the 1960s when computers shrunk from being room-sized to being sat on top of a desk.

Around 50 quantum computers have been built to date, and they all use different software – there is no quantum equivalent of Windows, IOS or Linux. The new project will deliver an OS that allows the same quantum software to run on different types of quantum computing hardware.

LONDON – Newport Wafer Fab, the U.K.’s largest chip producer, is set to be acquired by Chinese-owned semiconductor company Nexperia for around £63 million ($87 million) next week, according to two sources close to the deal who asked to remain anonymous because the information is not yet public.

Nexperia, a Dutch firm that is 100%-owned by China’s Wingtech Technology, told CNBC on Friday that the deal talks are ongoing.

Located in Newport, South Wales, privately-held NWF’s chip plant dates back to 1982 and it is one of just a handful of semiconductor fabricators in the U.K.

“Cannabis may contribute to increased risk for mental disorders, which has actually been shown in schizophrenia,” Penzes said. “Conversely, cannabis could be beneficial in some brain disorders, which prompted trials of medical marijuana in patients with autism.”


Summary: Findings reveal a role the endocannabinoid system plays in a range of psychiatric disorders, including schizophrenia, bipolar disorder, and ASD.

Source: Northwestern University

Northwestern Medicine scientists discovered an unexpected connection between a synapse protein that has been implicated in neuropsychiatric disorders and the endocannabinoid pathway, according to a study published in Biological Psychiatry.

Indiana University School of Medicine researchers are developing a new, noninvasive brain stimulation technique to treat neurological disorders, including pain, traumatic brain injury (TBI), epilepsy, Parkinson’s disease, Alzheimer’s disease and more.

“Given the increasing use of stimulation in human brain study and treatment of neurological diseases, this research can make a big impact on physicians and their patients,” said Xiaoming Jin, Ph.D., associate professor of anatomy, cell biology and physiology.

When someone experiences a , nerve injury, or neurodegeneration, such as in epilepsy and TBI, there is damage to the brain which can lead to loss and damage of nerve or neurons and development of hyperexcitability that underlies some neurological disorders such as neuropathic pain and epilepsy.

Researchers from Harvard University and the Massachusetts Institute of Technology, both based in Cambridge, Mass., have created small diagnostic biosensors that can be inserted into face masks and can diagnose COVID-19 within 90 minutes, The Mercury News reported June 29.

The insertable biosensors detect the virus from a wearer’s breath, producing easy to read results similar to those of an at-home pregnancy test. If the coronavirus is present, the system changes the pattern of lines in the readout strip.

To activate the test, the wearer pushes a button on the mask to release a small amount of water into the system, which activates the test.

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The story of humanity is progress, from the origins of humanity with slow disjointed progress to the agricultural revolution with linear progress and furthermore to the industrial revolution with exponential almost unfathomable progress.

This accelerating rate of change of progress is due to the compounding effect of technology, in which it enables countless more from 3D printing, autonomous vehicles, blockchain, batteries, remote surgeries, virtual and augmented reality, robotics – the list can go on and on. These devices in turn will lead to mass changes in society from energy generation, monetary systems, space colonization, automation and much more!

This is only the Beginning.


Quantum physicist Mario Krenn remembers sitting in a café in Vienna in early 2016, poring over computer printouts, trying to make sense of what MELVIN had found. MELVIN was a machine-learning algorithm Krenn had built, a kind of artificial intelligence. Its job was to mix and match the building blocks of standard quantum experiments and find solutions to new problems. And it did find many interesting ones. But there was one that made no sense.

“The first thing I thought was, ‘My program has a bug, because the solution cannot exist,’” Krenn says. MELVIN had seemingly solved the problem of creating highly complex entangled states involving multiple photons (entangled states being those that once made Albert Einstein invoke the specter of “spooky action at a distance”). Krenn and his colleagues had not explicitly provided MELVIN the rules needed to generate such complex states, yet it had found a way. Eventually, he realized that the algorithm had rediscovered a type of experimental arrangement that had been devised in the early 1990s. But those experiments had been much simpler. MELVIN had cracked a far more complex puzzle.

“When we understood what was going on, we were immediately able to generalize [the solution],” says Krenn, who is now at the University of Toronto. Since then, other teams have started performing the experiments identified by MELVIN, allowing them to test the conceptual underpinnings of quantum mechanics in new ways. Meanwhile Krenn, Anton Zeilinger of the University of Vienna and their colleagues have refined their machine-learning algorithms. Their latest effort, an AI called THESEUS, has upped the ante: it is orders of magnitude faster than MELVIN, and humans can readily parse its output. While it would take Krenn and his colleagues days or even weeks to understand MELVIN’s meanderings, they can almost immediately figure out what THESEUS is saying.