Toggle light / dark theme

Encouraging Mid Trial data update! Great to know Dr. Katcher is applying for IRB approval for their human clinical trial for E5.


In this video we provide an update on Dr. Katcher’s experiment where he is treating rats with E5 (formerly called Elixer) on a regular schedule to see how long they will live for. Dr Katcher’s team have kindly provided some intermediate updates that we share in the video.
0:00 — 00:50 Introduction.
00:51 — 04:02 Project Background/Overview.
04:03 — Project Update.

Papers referred to in this newsletter.

The largest salt lake in the Western Hemisphere is shrinking rapidly. Left alone, the lake’s footprint would span 2100 square miles — more than three times the area of Houston. An analysis published last year showed that water siphoned off the rivers that feed the natural wonder had reduced its level by 11 feet, depleting the lake area by more than half.

The trouble trickles up the food chain. The Utah Geological Survey openly expressed its fear Thursday that the shrinking lake levels threaten to kill microbialites — underwater reef-like mounds that help feed brine flies, brine shrimp and, thus, the 338 species of birds that visit each year.


Great Salt Lake is also known as America’s Dead Sea — owing to a likeness to its much smaller Middle Eastern counterpart — but scientists worry the moniker could soon take new meaning.

Salvatore Vitale describes how gravitational-wave signals suggest black holes completely devoured their companion neutron stars.

Recently, an international team of scientists, including researchers at MIT, announced the detection of a new kind of astrophysical system: a collision between a black hole and a neutron star — two of the densest, most exotic objects in the universe.

Scientists have detected signals of colliding black holes, and colliding neutron stars, but had not confirmed a merging of a black hole with a neutron star until now. In a study appearing today in The Astrophysical Journal Letters, the scientists report observing not just one, but two such rare events, each of which gave off gravitational waves that reverberated across a large swath of the universe before reaching Earth in January 2020, just 10 days apart.

SEOUL—The smartphone industry is showing battle scars from the world-wide chip crunch.

Shipments are slowing and customers are seeing their first significant price increases in years. Some companies have had to scale back production and delay new releases. All this has halted what had been a strong start to the year.

Smartphone makers, for much of the year, avoided the parts disruptions faced in the auto, personal computer and home-appliance industries. Phone manufacturers purchase key parts roughly a half a year in advance, but now those stockpiles have shrunk.

TAIPEI —Taiwan Semiconductor Manufacturing Co Ltd (TSMC) signalled on Thursday plans to build new factories in the United States and Japan, riding on a pandemic-led surge in demand for chips that power smartphones, laptops and cars.

TSMC, which posted record quarterly sales and forecast higher revenue for the current quarter, said it will expand production capacity in China and does not rule out the possibility of a “second phase” expansion at its $12 billion factory in Arizona.

The world’s largest contract chipmaker and a major Apple supplier also said it is currently reviewing a plan to set up a speciality technology wafer fabrication plant, or fab, in Japan.