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Vanderbilt University researchers, led by alumnus Bryan Gitschlag, have uncovered groundbreaking insights into the evolution of mitochondrial DNA (mtDNA). In their paper in Nature Communications titled “Multiple distinct evolutionary mechanisms govern the dynamics of selfish mitochondrial genomes in Caenorhabditis elegans,” the team reveals how selfish mtDNA, which can reduce the fitness of its host, manages to persist within cells through aggressive competition or by avoiding traditional selection pressures. The study combines mathematical models and experiments to explain the coexistence of selfish and cooperative mtDNA within the cell, offering new insights into the complex evolutionary dynamics of these essential cellular components.

Gitschlag, an alumnus of Vanderbilt University, conducted the research while in the lab of Maulik Patel, assistant professor of biological sciences. He is now a postdoctoral researcher at Cold Spring Harbor Laboratory in David McCandlish’s lab. Gitschlag collaborated closely with fellow Patel Lab members, including James Held, a recent PhD graduate, and Claudia Pereira, a former staff member of the lab.

Hoboken, April 20, 2024. Daniel Dennett’s death feels like the end of an era, the era of ultra-materialist, ultra-Darwinian, swaggering, know-it-all scientism. Who’s left? Dawkins? Dennett isn’t as smart as he thinks he is, I liked to say, because no one is. He lacked the self-doubt gene, but he forced me to doubt myself, he made me rethink what I think, and what more can you ask of a philosopher? I first encountered Dennett’s in-your-face brilliance in 1981 when I read The Mind’s I, and his name popped up at a consciousness shindig I attended just last week. To honor Dennett, I’m posting a free, revised version of my 2017 critique of his claim that consciousness is an “illusion.” I’m also coining a phrase, “the Dennett Paradox,” explained below.— John Horgan

Of all the odd notions to emerge from debates over consciousness, the oddest is that it doesn’t exist, at least not in the way we think it does. It is an illusion, like “Santa Claus” or “American democracy.”

Descartes said consciousness is the one undeniable fact of our existence, and I find it hard to disagree. I’m conscious right now, as I type this sentence, and you are presumably conscious as you read it (although I can’t be absolutely sure).

AROMAS, Calif. (AP) — An earthquake registering magnitude 4.2 shook part of central California early Sunday, the United States Geological Survey reported.

The earthquake was detected at 2:47 a.m. local time about 2 miles (3.2 kilometers) northwest of Aromas with a depth of 7.4 kilometers (4.59 miles), the science agency said on its website and in a social media post.

There were no immediate reports of injuries or major property damage, according to local media.

Sleep, fasting, exercise, green porridge, black coffee, a healthy social life—there is an abundance of advice out there on how to live a good, long life. Researchers are working hard to determine why some people live longer than others, and how we get the most out of our increasingly long lives.

Now researchers from the Center for Healthy Aging, Department of Cellular and Molecular Medicine at the University of Copenhagen have discovered that a particular protein known as OSER1 has a great influence on longevity. The research is published in the journal Nature Communications.

“We identified this protein that can extend longevity. It is a novel pro-longevity factor, and it is a protein that exists in various animals, such as fruit flies, nematodes, silkworms, and in humans,” says Professor Lene Juel Rasmussen, senior author behind the new study.