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Jun 9, 2021

Researchers may have sequenced the ‘final unknown’ of the human genome

Posted by in category: biotech/medical

An international team of scientists says it has sequenced and assembled the entirety of the human genome, including parts that were missed in the sequencing of the first human genome two decades ago.

The claim, if confirmed, surpasses the achievement laid out by leaders from the Human Genome Project and Celera Genomics on the White House lawn in 2000, when they announced the sequencing of the first draft human genome. That historic draft, and subsequent human DNA sequences, have all missed about 8% of the genome.

The sequencing of the new genome fills in these gaps using new technology. It has different limitations, however, including the type of cell line that the researchers used in order to speed up their effort.

Jun 9, 2021

On This Day in Space! June 8, 1959: X-15 makes first glide flight

Posted by in categories: economics, energy, military, space

Because it was, 62 years ago, the first fully reusable space vehicle, two stages, both reusable. The same concept of Virgin Galactic SpaceShipTwo.

X15 made 200 flights at suborbital altitude, 100 km.

Continue reading “On This Day in Space! June 8, 1959: X-15 makes first glide flight” »

Jun 8, 2021

Segway (Yes, Segway) Is Making a Hybrid Motorcycle Worthy of All Your ‘Tron’ Fantasies

Posted by in categories: energy, transportation

The bike’s powertrain uses a fuel cell to turn gaseous hydrogen into electrical energy.


The engine setup holds its own, too. The Apex H2 will feature a hybrid powertrain that will convert gaseous hydrogen into electrical energy via a special fuel cell, reports New Atlas. Ninebot says the hydrogen-electric setup will be able to generate over 80 horsepower and rocket the bike from zero to 60 mph in less than four seconds. Considering that the original Segway—yes, the infamous two-wheel personal transporter favored by mall cops—topped out at 10 mph, that’s pretty impressive, even if it is slower than the Apex concept’s quoted top speed of 124 mph. Of course, there’s one key difference between the two bikes: The Apex H2 will be one of the rare concept vehicles you’ll be able to buy.

Continue reading “Segway (Yes, Segway) Is Making a Hybrid Motorcycle Worthy of All Your ‘Tron’ Fantasies” »

Jun 8, 2021

Arctic rotifer lives after 24,000 years in a frozen state

Posted by in categories: biological, chemistry

Bdelloid rotifers are multicellular animals so small you need a microscope to see them. Despite their size, they’re known for being tough, capable of surviving through drying, freezing, starvation, and low oxygen. Now, researchers reporting in the journal Current Biology on June 7 have found that not only can they withstand being frozen, but they can also persist for at least 24000 years in the Siberian permafrost and survive.

“Our report is the hardest proof as of today that multicellular animals could withstand tens of thousands of years in cryptobiosis, the state of almost completely arrested metabolism,” says Stas Malavin of the Soil Cryology Laboratory at the Institute of Physicochemical and Biological Problems in Soil Science in Pushchino, Russia.

The Soil Cryology Lab specializes in isolating from the ancient permafrost in Siberia. To collect samples, they use a in some of the most remote Arctic locations.

Jun 8, 2021

Aldehyde-stabilized cryopreservation

Posted by in categories: biotech/medical, chemistry, cryonics, finance, life extension, neuroscience

Circa 2015 brain immortality through aldehyde stabilized cryopreservation.


We describe here a new cryobiological and neurobiological technique, aldehyde-stabilized cryopreservation (ASC), which demonstrates the relevance and utility of advanced cryopreservation science for the neurobiological research community. ASC is a new brain-banking technique designed to facilitate neuroanatomic research such as connectomics research, and has the unique ability to combine stable long term ice-free sample storage with excellent anatomical resolution. To demonstrate the feasibility of ASC, we perfuse-fixed rabbit and pig brains with a glutaraldehyde-based fixative, then slowly perfused increasing concentrations of ethylene glycol over several hours in a manner similar to techniques used for whole organ cryopreservation. Once 65% w/v ethylene glycol was reached, we vitrified brains at −135 °C for indefinite long-term storage. Vitrified brains were rewarmed and the cryoprotectant removed either by perfusion or gradual diffusion from brain slices. We evaluated ASC-processed brains by electron microscopy of multiple regions across the whole brain and by Focused Ion Beam Milling and Scanning Electron Microscopy (FIB-SEM) imaging of selected brain volumes. Preservation was uniformly excellent: processes were easily traceable and synapses were crisp in both species. Aldehyde-stabilized cryopreservation has many advantages over other brain-banking techniques: chemicals are delivered via perfusion, which enables easy scaling to brains of any size; vitrification ensures that the ultrastructure of the brain will not degrade even over very long storage times; and the cryoprotectant can be removed, yielding a perfusable aldehyde-preserved brain which is suitable for a wide variety of brain assays.

Jun 8, 2021

First on CNN Business: Asia’s fake pork titan sets its sights on the next ‘big’ thing

Posted by in categories: business, food, space

OmniFoods is far from the only player breaking into the space. Last year, Nestlé announced its entrance into the category, rolling out a vegan tuna product in Switzerland. Impossible has also previously announced it was working on an alternative fish product.


OmniFoods, the Hong Kong startup best known for its fake pork product “OmniPork,” is jumping on what it sees as the next phenomenon: plant-based seafood.

In an announcement first shared with CNN Business, the company said Tuesday it is launching a new line of products that include alternatives to fish fillets, fish burgers and cuts of tuna.

Continue reading “First on CNN Business: Asia’s fake pork titan sets its sights on the next ‘big’ thing” »

Jun 8, 2021

Addmotor Motan M-66 R7 e-bike review: An easy-riding, fun electric moped

Posted by in categories: health, transportation

Electric bicycles in the rugged moped style are all over the place these days, and for good reason. Unlike fitness e-bikes that are often used for a combination of exercise and leisure riding, electric mopeds are built mostly for good old fashioned getting around. And the Addmotor M-66 R7 moped fully embodies that design ethos. It’s a transportation e-bike that will have you zipping around your city faster than a car and cheaper than a public transport season ticket.

Jun 8, 2021

Sleep Problems in Autism Linked to Glial Cells, Blood-Brain-Barrier and Serotonin

Posted by in categories: biotech/medical, health, neuroscience

Summary: A study in fruit fly models of autism reveals sleep disruption associated with the neurodevelopmental disorder is associated with elevated levels of serotonin. The origin of the higher levels of serotonin was discovered to be in glial cells in the blood-brain barrier.

Source: Radboud University.

Bad sleep causes severe health issues and affects our ability to concentrate, memorize, and cope with challenging situations. Individuals with neurodevelopmental disorders such as autism and intellectual disability, frequently suffer from sleep problems. However, little is known about their underlying mechanisms.

Jun 8, 2021

Subatomic particle seen changing to antiparticle and back

Posted by in category: particle physics

Physicists have proved that a subatomic particle can switch into its antiparticle alter-ego and back again, in a new discovery revealed today.

The extraordinarily precise measurement was made by UK researchers using the Large Hadron Collider beauty (LHCb) experiment at CERN.

It has provided the first evidence that mesons can change into their antiparticle and back again.

Jun 8, 2021

How an Obscure Company Took Down Big Chunks of the Internet

Posted by in category: internet

Early Tuesday morning, large portions of the web sputtered out for about an hour. The downed sites shared no obvious theme or geography; the outages were global, and they hit everything from Reddit to Spotify to The New York Times. (And yes, also WIRED.) In fact, the only thing they have in common is Fastly, a content-delivery network (CDN) provider whose predawn hiccup reverberated across the internet.

You may not have heard of Fastly, but you likely interact with it in some fashion every time you go online. Along with Cloudflare and Akamai, it’s one of the biggest CDN providers in the world. And while Fastly has been vague about what specific glitch caused Tuesday’s worldwide disruptions, the incident offers a stark reminder of how fragile and interconnected internet infrastructure can be, especially when so much of it hinges on a handful of companies that operate largely outside of public awareness.