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Jul 1, 2020

Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection

Posted by in category: biotech/medical

Pigs are intermediate hosts for the generation of pandemic influenza virus. Thus, systematic surveillance of influenza viruses in pigs is a key measure for prewarning the emergence of the next pandemic influenza. Here, we identified a reassortant EA H1N1 virus possessing pdm/09 and TR-derived internal genes, termed as G4 genotype, which has become predominant in swine populations since 2016. Similar to pdm/09 virus, G4 viruses have all the essential hallmarks of a candidate pandemic virus. Of concern is that swine workers show elevated seroprevalence for G4 virus. Controlling the prevailing G4 EA H1N1 viruses in pigs and close monitoring in human populations, especially the workers in swine industry, should be urgently implemented.

Pigs are considered as important hosts or “mixing vessels” for the generation of pandemic influenza viruses. Systematic surveillance of influenza viruses in pigs is essential for early warning and preparedness for the next potential pandemic. Here, we report on an influenza virus surveillance of pigs from 2011 to 2018 in China, and identify a recently emerged genotype 4 (G4) reassortant Eurasian avian-like (EA) H1N1 virus, which bears 2009 pandemic (pdm/09) and triple-reassortant (TR)-derived internal genes and has been predominant in swine populations since 2016. Similar to pdm/09 virus, G4 viruses bind to human-type receptors, produce much higher progeny virus in human airway epithelial cells, and show efficient infectivity and aerosol transmission in ferrets. Moreover, low antigenic cross-reactivity of human influenza vaccine strains with G4 reassortant EA H1N1 virus indicates that preexisting population immunity does not provide protection against G4 viruses.

Jul 1, 2020

Astronauts Finalize Preps Before Wednesday’s Battery Spacewalk

Posted by in category: space

The Expedition 63 crew is set for its second spacewalk on Wednesday at 7:35 a.m. EDT to continue upgrading International Space Station power systems.

Commander Chris Cassidy will lead the spacewalk and exit the Quest airlock in the U.S. spacesuit with the red stripes. He’ll be followed by Flight Engineer Bob Behnken in his spacesuit with no stripes.

Both astronauts are being joined today by Flight Engineer Doug Hurley as they finalize procedure reviews, organize tools and perform suit leak checks before tomorrow’s spacewalk. Hurley will be on duty helping the spacewalkers in and out their spacesuits and monitoring the excursion. Roscosmos cosmonaut Ivan Vagner will assist the NASA trio on Wednesday.

Jul 1, 2020

After Tuesday’s launch, SpaceX expands its fleet of used rockets [Updated]

Posted by in category: space travel

SpaceX has gotten good enough at reuse that it’s building fewer rockets.

Jul 1, 2020

Archer Report- Sharif Rana, World Talent Economy Forum

Posted by in category: economics

https://www.youtube.com/watch?v=FC-Fh3Igv9M&feature=youtu.be

Steele Hawes’ Archer Report with special guest Sharif Uddin Ahmed Rana.

Jul 1, 2020

Welcome to Cloud City: The case for going to Venus, not Mars

Posted by in categories: Elon Musk, space travel

https://vimeo.com/401171025

I know Elon Musk believes Mars is the promised land that we should try to move humans to but what about Venus?


A growing group of scientists want to float above our sister planet before we conquer the red one.

Jul 1, 2020

Airlifters Packed With Paratroopers Just Practiced A Sudden Long-Range Invasion Of Guam

Posted by in category: futurism

The operation saw Air Force C-17s laden with airborne troops fly thousands of miles across the Pacific to raid Andersen AFB.

Jul 1, 2020

The biodiversity leader who is fighting for nature amid a pandemic

Posted by in category: biotech/medical

In an interview with Nature, Elizabeth Maruma Mrema, the new head of the United Nations Convention on Biodiversity, acknowledged that it would be difficult to set a single target because biodiversity is multifaceted. But, if the community succeeds in making it work, she adds: “that will be the best result possible because then it becomes a song everyone will sing, and that everybody can align with to deliver that one key message.”


Elizabeth Mrema has a mighty task ahead of her, leading countries as they negotiate new biodiversity targets.

Jun 30, 2020

White House ordered NIH to cancel coronavirus research funding, Fauci says

Posted by in category: biotech/medical

China-develops-worlds-first-coronavirus-vaccine.


The research was the target of a conspiracy theory about the origin of the new coronavirus.

Continue reading “White House ordered NIH to cancel coronavirus research funding, Fauci says” »

Jun 30, 2020

Is Plant ‘Intelligence’ Just a Human Fantasy?

Posted by in category: neuroscience

Although plants make up over 80% of the biomass on Earth, for centuries they have been thought of as inanimate and passive things. Researchers even coined the term “plant blindness” to refer to a cognitive bias that literally makes our brains zone out plants in our view and underestimate their importance.

Jun 30, 2020

How a protein’s small change leads to big trouble for cells

Posted by in categories: biotech/medical, chemistry, neuroscience

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don’t fold the way they’re supposed to, it can lead to the development of diseases such as cancer.

Researchers at the Sloan Kettering Institute have uncovered important findings about what causes chaperones to malfunction as well as a way to fix them when they go awry. The discovery points the way to a new approach for developing targeted drugs for cancer and other diseases, including Alzheimer’s disease.

“Our earlier work showed that defects in chaperones could lead to widespread changes in cells, but no one knew exactly how it happened,” says SKI scientist Gabriela Chiosis, senior author of a study published June 30 in Cell Reports. “This paper finally gets into the nuts and bolts of that biochemical mechanism. I think it’s a pretty big leap forward.”