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Hoboken, April 20, 2024. Daniel Dennett’s death feels like the end of an era, the era of ultra-materialist, ultra-Darwinian, swaggering, know-it-all scientism. Who’s left? Dawkins? Dennett isn’t as smart as he thinks he is, I liked to say, because no one is. He lacked the self-doubt gene, but he forced me to doubt myself, he made me rethink what I think, and what more can you ask of a philosopher? I first encountered Dennett’s in-your-face brilliance in 1981 when I read The Mind’s I, and his name popped up at a consciousness shindig I attended just last week. To honor Dennett, I’m posting a free, revised version of my 2017 critique of his claim that consciousness is an “illusion.” I’m also coining a phrase, “the Dennett Paradox,” explained below.— John Horgan

Of all the odd notions to emerge from debates over consciousness, the oddest is that it doesn’t exist, at least not in the way we think it does. It is an illusion, like “Santa Claus” or “American democracy.”

Descartes said consciousness is the one undeniable fact of our existence, and I find it hard to disagree. I’m conscious right now, as I type this sentence, and you are presumably conscious as you read it (although I can’t be absolutely sure).

Continue reading “Consciousness and the Dennett Paradox” | >

AROMAS, Calif. (AP) — An earthquake registering magnitude 4.2 shook part of central California early Sunday, the United States Geological Survey reported.

The earthquake was detected at 2:47 a.m. local time about 2 miles (3.2 kilometers) northwest of Aromas with a depth of 7.4 kilometers (4.59 miles), the science agency said on its website and in a social media post.

There were no immediate reports of injuries or major property damage, according to local media.

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Sleep, fasting, exercise, green porridge, black coffee, a healthy social life—there is an abundance of advice out there on how to live a good, long life. Researchers are working hard to determine why some people live longer than others, and how we get the most out of our increasingly long lives.

Now researchers from the Center for Healthy Aging, Department of Cellular and Molecular Medicine at the University of Copenhagen have discovered that a particular protein known as OSER1 has a great influence on longevity. The research is published in the journal Nature Communications.

“We identified this protein that can extend longevity. It is a novel pro-longevity factor, and it is a protein that exists in various animals, such as fruit flies, nematodes, silkworms, and in humans,” says Professor Lene Juel Rasmussen, senior author behind the new study.

Continue reading “Newly discovered Gene may Influence Longevity in Humans” | >

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Light momentum turns pure silicon from an indirect to a direct bandgap semiconductor https://phys.org/news/2024-09-momentum-pure-silicon-indirect-bandgap.html.

Original Paper https://arxiv.org/pdf/2304.

Continue reading “Light momentum turns pure silicon from an indirect to a direct bandgap semiconductor” | >

Macroautophagy (hereafter autophagy) is a cellular recycling process that degrades cytoplasmic components, such as protein aggregates and mitochondria, and is associated with longevity and health in multiple organisms. While mounting evidence supports that autophagy declines with age, the underlying molecular mechanisms remain unclear. Since autophagy is a complex, multistep process, orchestrated by more than 40 autophagy-related proteins with tissue-specific expression patterns and context-dependent regulation, it is challenging to determine how autophagy fails with age. In this review, we describe the individual steps of the autophagy process and summarize the age-dependent molecular changes reported to occur in specific steps of the pathway that could impact autophagy.

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