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The structural integrity of the brain’s white matter as measured with an advanced MRI technique is lower in cognitively normal people who carry a genetic mutation associated with Alzheimer’s disease than it is in non-carriers, according to a study in Radiology. Researchers said the findings show the promise of widely available imaging techniques in helping to understand early structural changes in the brain before symptoms of dementia become apparent.

People who carry the autosomal dominant Alzheimer disease (ADAD) mutation have a higher risk of Alzheimer’s disease, a type of dementia that affects about one in nine people in the United States. The mutation is linked to a buildup of abnormal protein called amyloid-beta in the brain that affects both the gray matter and the signal-carrying white matter.

“It’s thought that the amyloid deposition in the gray matter could disrupt its function, and as a result the white matter won’t function correctly or could even atrophy,” said study lead author Jeffrey W. Prescott, M.D., Ph.D., neuroradiologist at the MetroHealth Medical Center in Cleveland.

German air taxi manufacturer Volocopter launched a self-developed heavy-duty drone in public for the first time on Tuesday at the ITS World Congress in Hamburg.

In cooperation with German logistics provider DB Schenker, the company demonstrated the integration of the VoloDrone into logistics supply chains.

The test flight, which lasted about three minutes, took place around the harbor area of the city in northern Germany. The ITS congress is an international digital transport event.

As technology rapidly progresses, some proponents of artificial intelligence believe that it will help solve complex social challenges and offer immortality via virtual humans.

But AI’s critics are sounding the alarm, going so far as to call its development an “existential threat” to mankind. Is this the stuff of science fiction? Could the “Terminator” become reality, or will these fears prevent the next technological revolution?

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Findings from study believed to be largest of its kind contradict smaller studies showing treatment’s promise.

Regular doses of the hormone oxytocin do not appear to overcome deficits in social functioning among children with autism spectrum disorder (ASD), suggests a study funded by the National Institutes of Health. The findings contradict earlier reports that indicated the hormone could alleviate the difficulties in social functioning characteristic of ASD. Oxytocin is associated with empathy and social bonding. The study was conducted by Linmarie Sikich, M.D., of Duke University, and colleagues. It appears in the New England Journal of Medicine.

Funding was provided by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and National Center for Advancing Translational Sciences.

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Microsoft’s blog post on Megatron-Turing says the algorithm is skilled at tasks like completion prediction, reading comprehension, commonsense reasoning, natural language inferences, and word sense disambiguation. But stay tuned—there will likely be more skills added to that list once the model starts being widely utilized.

GPT-3 turned out to have capabilities beyond what its creators anticipated, like writing code, doing math, translating between languages, and autocompleting images (oh, and writing a short film with a twist ending). This led some to speculate that GPT-3 might be the gateway to artificial general intelligence. But the algorithm’s variety of talents, while unexpected, still fell within the language domain (including programming languages), so that’s a bit of a stretch.

However, given the tricks GPT-3 had up its sleeve based on its 175 billion parameters, it’s intriguing to wonder what the Megatron-Turing model may surprise us with at 530 billion. The algorithm likely won’t be commercially available for some time, so it’ll be a while before we find out.