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Blood test can detect more than 50 kinds of cancer, new study suggests

Made by U.S. pharmaceutical company Grail, the Galleri test aims to find fragments of DNA in a person’s blood that can indicate the presence of a cancerous tumor. Among the cancers that the test can detect, many have no current screening programs.

The PATHFINDER 2 study included more than 36,000 people aged 50 and older who had no cancer symptoms. In participants who were followed for more than a year, the test caught some 40.4% of cancer cases. For those who got a positive result on the Galleri test, 61.6% of them went on to be diagnosed with cancer—an improvement over previous trials of the test.

The results were presented on Saturday at the European Society for Medical Oncology meeting in Berlin, and have yet to be published in a peer-reviewed journal.

🌿 International Conference “Anti-Aging: Science and Practice of Healthy Longevity” —

October 21–22, 2025 (Online) 🌿

Dear colleagues and friends.

We are pleased to invite you to the International Scientific Conference “Anti-Aging: Science and Practice of Healthy Longevity”, organized by the Gerontology Section of the Moscow Society of Naturalists (MOIP) at Lomonosov Moscow State University, with the support of the Gerontology Society of the Ural Branch of the Russian Academy of Sciences (URAN).

📅 Dates: October 21–22, 2025 🕛 Time: 12:00–16:00 (Moscow time) 💻 Format: Online participation (free of charge) 🗣️ Working language: Russian.

🔹 October 21 — “Hypoxic Training (Therapy): Modern Aspects of Healthy Longevity Medicine” 🔹 October 22 — “Fundamental and Clinical Gerontology as the Basis of Healthy Longevity Medicine”

The conference will feature leading scientists from Russia, Germany, Belarus, Kyrgyzstan and other countries. Topics include: • Hypoxic therapy and adaptive mechanisms; • Geroprotection and the biology of aging; • Epigenetic reprogramming and cellular rejuvenation; • Applied aspects of active and healthy longevity.

🔗 Connection links: • Day 1 (October 21): https://my.mts-link.ru/j/38630705/5798697072

Continue reading “🌿 International Conference “Anti-Aging: Science and Practice of Healthy Longevity” —” | >

Cryosphere Chat ft. Emil Kendziorra — Tales from Biostasis 2025, Our Near Death Experiences

The gang catches up with Emil Kendziorra after the Biostasis 2025 conference at the European Biostasis Foundation. Watch it on YouTube here. Topics covered include:

• How to get a Tomorrow Bio ambulance in your hometown.
• Tomorrow Bio’s plan to collect brain samples to check ultra-structure preservation in its cryonics patients — and how it will respond to what it finds.
• What’s new and what’s next for Tomorrow Bio.
• Our near death experiences.

Links:
• Cryosphere Discord Server: / discord.
• Cryonics Subreddit: / cryonics.

Scientists create a metal that does not break, rust, or melt

A new alloy made from chromium, molybdenum, and silicon – three metals known for strength, heat tolerance, and stability – breaks expectations by staying tough at room temperature while resisting oxidation even under extreme heat.

The study reports room temperature ductility, oxidation resistance in air to 1,100 C, and a melting point near 2,000 C.

A Tiny Peptide Can Freeze Parkinson’s Proteins Before They Turn Toxic

As Parkinson’s disease progresses, harmful protein clumps build up in the brain, blocking communications between neurons and killing them off – but what if we could prevent these clusters from forming?

Researchers led by a team from the University of Bath in the UK have achieved just that in a basic worm model of Parkinson’s. They engineered a peptide, a small amino acid chain, to essentially keep a protein called alpha-synuclein locked in its healthy shape. This prevented the misfolding that leads to clumps.

The potential treatment checks several important boxes: it’s durable, and it can survive inside cells without causing any toxic side effects.

NVIDIA Embraces the ‘Made in USA’ Narrative, As Jensen Huang Unveils the First Blackwell Chip Wafer Produced by TSMC Arizona

NVIDIA’s CEO has revealed that TSMC has produced the first Blackwell chip wafer in America, a massive development towards the future of manufacturing in the nation.

Since the Trump administration took office, efforts to bring manufacturing back to the US have influenced almost every tech giant, with NVIDIA leading the way. The firm announced plans to invest $500 billion in American manufacturing, prompting suppliers like Foxconn and Quanta to set up manufacturing facilities in the US. In a blog post shared by Team Green, it is revealed that TSMC Arizona has begun manufacturing Blackwell on American soil, and Jensen Huang himself paid a visit to Phoenix to celebrate this massive achievement.

Sean Carroll: Can we ever escape the logic of a clockwork universe?

What if the universe is a machine, and every moment in our past, present, and future is already encoded in the positions of its particles?

Physicist Sean Carroll explores the unsettling implications of classical mechanics, from Newton’s laws to Laplace’s thought experiment, showing how determinism challenges the very idea of free will.

Leukemia cells evade treatment by reshaping their mitochondria, researchers discover

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients—and found a potential way to overcome that resistance.

Team members identified a protein that lets reshape their energy-producing mitochondria in ways that protect them from venetoclax (brand name, Venclexta), a for acute myeloid leukemia that often loses effectiveness after prolonged use.

Blocking that protein with experimental compounds in mice with human acute myeloid leukemia restored the drug’s effectiveness and prolonged survival.

Lab-grown brains with all major cell types support next-generation therapy research

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown from individual donors’ induced pluripotent stem cells, these models—dubbed Multicellular Integrated Brains (miBrains)—replicate key features and functions of human brain tissue, are readily customizable through gene editing, and can be produced in quantities that support large-scale research.

Although each unit is smaller than a dime, miBrains may be worth a great deal to researchers and drug developers who need more complex living lab models to better understand brain biology and treat diseases.

“The miBrain is the only in vitro system that contains all six major cell types that are present in the human brain,” said Li-Huei Tsai, Picower Professor, director of The Picower Professor of Learning and Memory, and senior author of the study describing miBrains, published in the Proceedings of the National Academy of Sciences.

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