Lifeboat Foundation

Cosmologists love universe simulations. Even models covering hundreds of millions of light years can be useful for understanding fundamental aspects of cosmology and the early universe. There’s just one problem – they’re extremely computationally intensive. A 500 million light year swath of the universe could take more than 3 weeks to simulate… Now, scientists led by Yin Li at the Flatiron Institute have developed a way to run these cosmically huge models 1000 times faster. That 500 million year light year swath could then be simulated in 36 minutes.

Older algorithms took such a long time in part because of a tradeoff. Existing models could either simulate a very detailed, very small slice of the cosmos or a vaguely detailed larger slice of it. They could provide either high resolution or a large area to study, not both.

To overcome this dichotomy, Dr. Li turned to an AI technique called a generative adversarial network (GAN). This algorithm pits two competing algorithms again each other, and then iterates on those algorithms with slight changes to them and judges whether those incremental changes improved the algorithm or not. Eventually, with enough iterations, both algorithms become much more accurate naturally on their own.

Only one in three fertilizations leads to a successful pregnancy. Many embryos fail to progress beyond early development. Cell biologists at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen (Germany), together with researchers at the Institute of Farm Animal Genetics in Mariensee and other international colleagues, have now developed a new model system for studying early embryonic development. With the help of this system, they discovered that errors often occur when the genetic material from each parent combines immediately after fertilization. This is due to a remarkably inefficient process.

Human somatic cells typically have 46 chromosomes, which together carry the genetic information. These chromosomes are first brought together at fertilization, 23 from the father’s sperm, and 23 from the mother’s egg. After fertilization, the parental chromosomes initially exist in two separate compartments, known as pronuclei. These pronuclei slowly move towards each other until they come into contact. The pronuclear envelopes then dissolve, and the parental chromosomes unite.

The majority of human embryos, however, end up with an incorrect number of chromosomes. These embryos are often not viable, making erroneous genome unification a leading cause of miscarriage and infertility.

Researchers at ETH Zurich have succeeded in turning specially prepared graphene flakes either into insulators or into superconductors by applying an electric voltage. This technique even works locally, meaning that in the same graphene flake regions with completely different physical properties can be realized side by side.

The production of modern electronic components requires materials with very diverse properties. There are isolators, for instance, which do not conduct electric current, and superconductors which transport it without any losses. To obtain a particular functionality of a component one usually has to join several such materials together. Often that is not easy, in particular when dealing with nanostructures that are in widespread use today.

A team of researchers at ETH Zurich led by Klaus Ensslin and Thomas Ihn at the Laboratory for Solid State Physics have now succeeded in making a material behave alternately as an insulator or as a superconductor – or even as both at different locations in the same material – by simply applying an electric voltage. Their results have been published in the scientific journal Nature Nanotechnology. The work was supported by the National Centre of Competence in Research QSIT (Quantum Science and Technology).

Many organisms and tissues display the ability to heal and regenerate as needed for normal physiology and as a result of pathogenesis. However, these repair activities can also be observed at the single-cell level. The physical and molecular mechanisms by which a cell can heal membrane ruptures and rebuild damaged or missing cellular structures remain poorly understood. This Review presents current understanding in wound healing and regeneration as two distinct aspects of cellular self-repair by examining a few model organisms that have displayed robust repair capacity, including Xenopus oocytes, Chlamydomonas, and Stentor coeruleus. Although many open questions remain, elucidating how cells repair themselves is important for our mechanistic understanding of cell biology. It also holds the potential for new applications and therapeutic approaches for treating human disease.

Cells are generally soft and easily damaged. However, many can repair themselves after being punctured, torn, or even ripped in half when damaged during the ordinary wear and tear of normal physiology or as a result of injury or pathology. A cell is like a spacecraft: When it is punctured, cytoplasm spills out like oxygen escaping from a damaged space module. Like Apollo 13, a damaged cell cannot rely on anyone to fix it. It must repair itself, first by stopping the loss of cytoplasm, and then regenerate by rebuilding structures that were damaged or lost. Knowledge of how single cells repair and regenerate themselves underpins our mechanistic understanding of cell biology and could guide treatments for conditions involving cellular damage.

A standard question that students are asked is to define what it means to be alive. This is surprisingly hard to answer in a precise way, but surely one of the remarkable features of living systems that distinguishes them from human-made machines is their ability to heal and repair themselves. At the multicellular level, repair and regeneration are effected by generating new cells to replace the ones that were lost. This type of repair thus ends up being a direct consequence of another basic feature of living systems—the ability of a cell to reproduce itself. No additional processes need to be invoked beyond cell division. At the single-cell level, it is much less obvious how self-repair is accomplished.

Pretty soon, you’ll start seeing this term on very expensive items.

New Material Absorbs and Stores Solar Energy ‘The light that is thus trapped can be released by making a small spark near the glass.’ — L. Sprague de Camp, 1940.

3D Printed Damascus Steel Now Possible ‘… lined with durite, that strange close-packed laboratory product.’ — Robert Heinlein, 1939.

As the digital revolution has now become mainstream, quantum computing and quantum communication are rising in the consciousness of the field. The enhanced measurement technologies enabled by quantum phenomena, and the possibility of scientific progress using new methods, are of particular interest to researchers around the world.

Recently two researchers at Tampere University, Assistant Professor Robert Fickler and Doctoral Researcher Markus Hiekkamäki, demonstrated that two–photon interference can be controlled in a near-perfect way using the spatial shape of the photon. Their findings were recently published in the prestigious journal Physical Review Letters.

“Our report shows how a complex light-shaping method can be used to make two quanta of light interfere with each other in a novel and easily tuneable way,” explains Markus Hiekkamäki.

TOKYO — India is rapidly closing the gap with China in minting new unicorns — privately held startups valued at $1 billion or more — highlighting growing investor appetite for tech startups in the country as the pandemic accelerates adoption of digital services.

Over the past year, 15 companies from India raised capital at a valuation of $1 billion or more for the first time, according to CB Insights and company announcements gathered by Nikkei Asia. Ten of them became unicorns in 2021. By comparison, only two of the 16 companies from China that joined the list over the past year did so in 2021, according to CB Insights.

A successful listing of online food delivery company Zomato, which recently filed a draft prospectus with India’s securities regulator, would set the stage for many of these unicorns to follow suit. Zomato, a loss-making company operating in a nascent industry once considered too risky to invest, is planning to raise 82.5 billion rupees ($1.1 billion), including through a pre-IPO placement.

Long-haul aviation, like everything else in the human world, needs to be totally decarbonized, and in the race to zero emissions for international airliners, liquid-hydrogen powertrains look like one of the only viable possibilities.

Airbus is working on a number of hydrogen-powered aircraft, and it’s just found a new angle on cryogenic liquid H2 fuel: using it to supercool the powertrain down to superconducting temperatures, possibly unlocking huge weight and efficiency savings.

O,.o! Woah

A never-ending detonation could be the key to hypersonic flight and space planes that can seamlessly fly from Earth into orbit. And now, researchers have recreated the explosive phenomenon in the lab that could make it possible.

Detonations are a particularly powerful kind of explosion that move outward faster than the speed of sound. The massive explosion that rocked the port of Beirut in Lebanon last August was a detonation, and the widespread destruction it caused demonstrates the huge amounts of energy they can produce.