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CHICAGO, Feb 4 (Reuters) — A study in monkeys pitting the current Moderna Inc (MRNA.O) COVID-19 booster against an Omicron-specific booster showed no significant differences in protection, suggesting an Omicron-specific booster may not be needed, U.S. government researchers reported on Friday.

The study involved monkeys vaccinated with two doses of Moderna’s vaccine who were dosed nine months later with either the conventional Moderna booster or one specifically targeting the Omicron variant.

The researchers tested various aspects of the animals’ immune responses and exposed them to the virus. They found both boosters produced “comparable and significant increases in neutralizing antibody responses” against all of the variants of concern, including Omicron, according to the study, posted on bioRxiv ahead of peer review.

Pioneering global generic medicine access to improve and extend people’s lives — keren haruvi snir-president, sandoz US, head of north america.


Keren Haruvi is President of Sandoz US and Head of their North America business (https://www.novartis.us/about-us/our-leadership/us-country-l
n-haruvi).

Sandoz is a division of the Novartis Group and a global leader in generic pharmaceuticals and biosimilars and was established in 2003, when Novartis united all of its generics businesses under the name Sandoz – a single global brand with a long history. Since then, Sandoz has grown into a leading global generics business with annual sales of approximately US$10 billion.

Connecting & enabling a smarter planet — alistair fulton, VP, wireless & sensing products, semtech.


Alistair Fulton (https://www.semtech.com/company/executive-leadership/alistair-fulton) is the Vice President and General Manager of Semtech’s Wireless and Sensing Products Group.

Semtech Corporation is a supplier of analog and mixed-signal semiconductors and advanced algorithms for consumer, enterprise computing, communications and industrial end-markets. It has 32 locations in 15 countries in North America, Europe, and Asia.

Delivering what has been so challenging to produce, researchers present an engineered analog of tooth enamel – an ideal model for designing biomimetic materials – designed to closely mimic the composition and structure of biological teeth’s hard mineralized outer layer. It demonstrates exceptional mechanical properties, they say.

Natural tooth enamel – the thin outer layer of our teeth – is the hardest biological material in the human body. It is renowned for its high stiffness, hardness, viscoelasticity, strength, and toughness and exhibits exceptional damage resistance, despite being only several millimeters thick.

Tooth enamel’s unusual combination of properties is a product of its hierarchical architecture – a complex structure made up of mostly hydroxyapatite nanowires interconnected by an amorphous intergranular phase (AIP) consisting of magnesium-substituted amorphous calcium phosphate. However, accurately replicating this type of hierarchical organization in a scalable abiotic composite has remained a challenge.