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If you’ve studied any physics you know that like charges repel and opposite charges attract. But why? It’s as though this thing — electric charge — is as fundamental a property of an object as its mass. It just sort of… is. Well it turns out if you dig deep enough, the fundamental-ness of charge unravels, and in many things, including mass itself, are unraveled with it.

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Continue reading “What If Charge is NOT Fundamental?” | >

Re-engineering clinical trials around participants — katie baca-motes, co-founder, scripps research digital trials center, scripps research.

Katie Baca-Motes, MBA, (https://www.scripps.edu/science-and-medicine/translational-i…aca-motes/) is Senior Director, Strategic Initiatives at the Scripps Research Translational Institute, and Co-Founder of the Scripps Research Digital Trials Center (https://digitaltrials.scripps.edu/).

Katie leads various initiatives, including launching their new Digital Trials Center, focusing on expanding the institute’s portfolio of decentralized clinical trial initiatives including: DETECT, a COVID-19 research initiative, PowerMom, a maternal health research program and PROGRESS, an upcoming T2 Diabetes/Precision Nutrition program, as well as overseeing the institute’s role in the NIH “All of Us” Research Program as a Participant Center.

The Scripps Research Translational Institute (SRTI), was founded in 2007 with the aim of individualizing healthcare by leveraging the remarkable progress being made in human genomics and combining it with the power of wireless digital technologies.

The Scripps Research Digital Trials Center, a part of SRTI, leads groundbreaking studies that address the world’s most pressing health concerns, by pioneering “site-less” clinical trials, leveraging rapidly evolving digital health technologies to re-engineer the clinical trial experience around the participant, rather than the research site.

Continue reading “Katie Baca-Motes — Co-Founder, Scripps Research Digital Trials Ctr — Re-Engineering Clinical Trials” | >

Koenigsegg calls the engine the Tiny Friendly Giant, or TFG for short, and it’s an apt name. The TFG is a 2.0-liter twin-turbo three-cylinder that makes 600 horsepower. At 300 horsepower per liter, the TFG’s specific output is far higher than anything ever seen in a road car. Koenigsegg says this is “light-years ahead of any other production three-cylinder today,” and he’s not wrong: The next most powerful triple is the 268-hp engine in the Toyota GR Yaris.

What’s even more unusual is that the TFG doesn’t have a camshaft. Instead, the engine uses technology from Koenigsegg’s sister company, Freevalve, with pneumatic actuators opening and closing each valve independently. I called company founder Christian von Koenigsegg to learn exactly how this unconventional engine works.

The Tiny Friendly Giant was designed specifically for the Gemera. Koenigsegg wanted something compact and lightweight, with big horsepower. Koenigsegg also decided to reverse the setup found in the hybrid Regera, where internal combustion provides the bulk of the total power output. In the Gemera, the majority of the power comes from electric motors, with the Gemera contributing some driving force as well as charging the hybrid drivetrain’s batteries.

The “Tiny Friendly Giant” is a game-changer for internal combustion. Christian von Koenigsegg explains this camless wonder.

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