By ten years.
An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart’s biological age by 10 years. The breakthrough, published in Cardiovascular Research and led by scientists at the University of Bristol and the MultiMedica Group in Italy, offers a potential target for patients with heart failure.
Associated with exceptional longevity, carriers of healthy mutant genes, like those living in blue zones of the planet, often live to 100 years or more and remain in good health. These individuals are also less prone to cardiovascular complications. Scientists believe the gene helps to keep their hearts young by protecting them against diseases linked to aging, such as heart failure.
In this new study, researchers demonstrate that one of these healthy mutant genes, previously proved particularly frequent in centenarians, can protect cells collected from patients with heart failure requiring cardiac transplantation.
One year ago, the Hunga Tonga-Hunga Ha’apai volcano erupted, causing widespread destruction to the Pacific Island Nation of Tonga. It spewed volcanic material up to 58 km into the atmosphere, brought a nearly 15 m tsunami that crashed ashore, destroying villages, and created a sonic boom that rippled around the world – twice. Even one year on, interest in the extraordinary explosive eruption remains. A sound artist has recently recreated the sonification of the underwater volcanic eruption using rayleigh signal intensity data provided by the Aeolus Virtual Research Environment platform. Using wind data obtained on one of its overpasses over the ash cloud of the Hunga Tonga explosion, Jamie Perera used an audio sample of one of the shock waves, time-stretched it into a ghostly tone, and assigned it to harmonic values transcribed from 90 Aeolus readings taken over a duration of approximately 15 minutes. The listener hears one reading every two seconds, in a harmonic range that spans six piano octaves, the highest of which can be heard at around 01:18 minutes when the readings show the eruption’s dust plume at its highest peak (over 20.5 km). The artistic intention behind the sonification was to evoke the otherworldly landscape of Hunga Tonga and other volcanoes. Sonification credit/copyright: 
