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Background: Diuretic-resistant fluid overload is a common problem encountered in hospitalized heart failure (HF) patients, with different interventions proposed to overcome it. Some studies have suggested that combining hypertonic saline with furosemide provided advantages over furosemide alone.

Study design: Systematic review and meta-analysis.

Setting: A comprehensive search of several databases from each database’s inception to March 17, 2020, and reference lists of retrieved articles and review articles in the field to identify additional publications.

The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It acts as a highly biocompatible natural scaffold and as a source of several types of stem cells and potent growth factors. It also serves as an effective nano-reservoir for drug delivery, thanks to its high entrapment properties. Over the past century, the use of the Amnio-M in the clinic has evolved from a simple sheet for topical applications for skin and corneal repair into more advanced forms, such as micronized dehydrated membrane, amniotic cytokine extract, and solubilized powder injections to regenerate muscles, cartilage, and tendons. This review highlights the development of the Amnio-M over the years and the implication of new and emerging nanotechnology to support expanding its use for tissue engineering and clinical applications. Graphical Abstract.

Meta, formerly Facebook, has said that its grand ambition of building the ultimate “metaverse” won’t be possible if there aren’t drastic improvements in today’s telecoms networks.

The metaverse is a buzzword that’s being hyped up as the next big thing in tech. Broadly speaking, the concept refers to a seamless virtual world where people can work, shop and play with their colleagues, friends and family.

Dan Rabinovitsj, VP of connectivity at Meta, told CNBC at the Mobile World Congress tech event Monday that home networks and cellular networks aren’t yet ready for the metaverse.

As hard as diamond and as flexible as plastic, highly sought-after diamond nanothreads would be poised to revolutionize our world—if they weren’t so difficult to make.

Recently, a team of scientists led by Carnegie’s Samuel Dunning and Timothy Strobel developed an original technique that predicts and guides the ordered creation of strong, yet flexible, , surmounting several existing challenges. The innovation will make it easier for scientists to synthesize the nanothreads—an important step toward applying the material to practical problems in the future. The work was recently published in the Journal of the American Chemical Society.

Diamond nanothreads are ultra-thin, one-dimensional carbon chains, tens of thousands of times thinner than a human hair. They are often created by compressing smaller carbon-based rings together to form the same type of bond that makes the hardest mineral on our planet.

Circa 2021


Small, affordable, ‘plug-and-play’ quantum computing is one step closer. An Australian startup has won $13 million to make its diamond-based computing cores shine. Now it needs to grow.

ANU research spinoff Quantum Brilliance has found a way to use synthetic diamonds to drive quantum calculations. Now it’s on a five-year quest to produce commercially viable Quantum Accelerators. The goal is a card capable of being plugged into any existing computer system similar to the way graphics cards are now.

“We’re not deluding ourselves,” says CEO Dr Andrew Horsley. “There’s still a lot of work to do. But we’ve now got a five-year pathway to produce a lunchbox-sized device”.