PX-478 improves insulin secretion in mouse and human organoid models of diabetes.
Captured CO2 products include non-petroleum fuels, vodka, perfume, foam, insulation, mattresses, and carbon fibre for buildings and cars.
Innovations in computing tech have improved the accuracy of DNA synthesis and enabled synthetic biology to work in the real world.
I don’t know about you, but I’m constantly looking for the “next big thing” in the stock market. And I think synthetic biology might just be it.
Why? If you invested just $10,000 into any of those world-changing stocks back in their early days, you’d have MILLIONS today. Forget the Iraq War, the housing crash, the European debt crisis. Forget the pandemic and the Russia-Ukraine war. Through it all, you’d have millions today.
Page Not Found — CBBC Newsround
Posted in robotics/AI
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BBC News.
Developers hope their ‘slime robot’ will one day be used to help find items that have been swallowed by accident.
The home of news and fun facts for kids. Find out what is going on, with stories, pictures and videos. Try a quiz or one of our free games.
I did a short youtube video discussing the space arena of the war in Ukraine.
Space War, what is it good for?
The space arena of the Russian invasion of Ukraine, spaceX, Starlink, Roscosmos and more… following an article I wrote on Quora with over 200k views.
The discovery that short peptides can form spontaneously on cosmic dust hints at more of a role for them in the origin of life, on Earth or elsewhere.
A miniature review of.
The risk of morbidity and mortality increases exponentially with age. Chronic inflammation, accumulation of DNA damage, dysfunctional mitochondria, and increased senescent cell load are factors contributing to this. Mechanistic investigations have revealed specific pathways and processes which, proposedly, cause age-related phenotypes such as frailty, reduced physical resilience, and multi-morbidity. Among promising treatments alleviating the consequences of aging are caloric restriction and pharmacologically targeting longevity pathways such as the mechanistic target of rapamycin (mTOR), sirtuins, and anti-apoptotic pathways in senescent cells. Regulation of these pathways and processes has revealed significant health-and lifespan extending results in animal models. Nevertheless, it remains unclear if similar results translate to humans. A requirement of translation are the development of age-and morbidity associated biomarkers as longitudinal trials are difficult and not feasible, practical, nor ethical when human life span is the endpoint. Current biomarkers and the results of anti-aging intervention studies in humans will be covered within this paper. The future of clinical trials targeting aging may be phase 2 and 3 studies with larger populations if safety and tolerability of investigated medication continues not to be a hurdle for further investigations.
As age increases, so does the susceptibility to a series of chronic diseases which ultimately result in fatal endings. This is such a basic part of life that we rarely consider if there is anything we can do to postpone it. So far, the principal of “one-disease-one-treatment” has brought medical sciences far but this line of thought may soon be outdated when it comes to aging related conditions. It is like fighting a many-headed monster: If one condition is treated successfully, another emerges shortly after. This point is illustrated as eradicating the two leading causes of death (cancer and cardiovascular disease) extends mean life span by 3.3 and 4 years, respectively (Arias et al., 2013). Interestingly, the gain of treating multiple diseases combined exceeds the sum of these numbers.
Aging is the greatest risk factor for most diseases likely because as aging progresses, cells and tissue undergo a series of processes which result in gradually declining functionality, accumulation of damage, increased inflammation, and cell death. If these processes are reversable or treatable, all aging related chronical diseases may potentially be simultaneously treated—or postponed—and healthy aging could be achieved. This approach to treating aging itself could effectively treat chronic diseases among the world’s elderly, shifting from treating symptoms of aging to treating the cause of it. The fact that the number and proportion of elderly people (65 years) is growing in every country in the world underlines the relevance of this field of research (World Population Prospects — Population Division, 2021).
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Code Jam
Posted in information science
Put your coding skills to the test as you work your way through multiple rounds of algorithmic coding puzzles for the title of Code Jam Champ and 15,000 USD.
I’m trying to recall a sci-fi short story that I once read, about a spacecraft that’s attempting to travel farther from Earth than anyone ever has before. As it gets farther away, the crew start to experience unexplained psychological and neurological symptoms. One by one, they eventually become catatonic and need to be cared for in the ship’s infirmary, while their crewmates desperately try to determine the cause.
The protagonist is the last person to be affected, and just as they are starting to succumb, they come up with a theory: human consciousness is not just an individual phenomenon, but is somehow dependent on the collective effect of all the other human minds on Earth. So as the ship leaves Earth’s “sphere of influence”, its passengers lose their consciousness and intelligence. Having realized this, the protagonist is barely able to program the autopilot to turn around, and the narration describes their descent into insanity and subsequent return to consciousness.
The title might have contained a reference to “closeness”, “distance”, “solitude”, “togetherness”, or something along those lines. I have a vague sense that the theme and style reminded me of David Brin’s work, but having looked through his bibliography, I don’t think it’s one of his stories.