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Discovery, Development & Delivery Of Safe, Effective & Affordable Vaccines For Global Public Health — Dr. Jerome H. Kim, M.D., Director General, International Vaccine Institute (IVI)

Dr. Jerome H. Kim, M.D., is the Director General of the International Vaccine Institute (IVI — https://www.ivi.int/), a nonprofit International Organization established in 1997 as an initiative of the United Nations Development Programme (UNDP), dedicated to the discovery, development and delivery of safe, effective and affordable vaccines for global public health.

IVI is headquartered in Seoul and hosted by the Republic of Korea with 36 member countries and the WHO on its treaty.

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The current state of affairs, however, is a bit more complicated. While quantum computers have officially gone from theory to fact—a remarkable achievement—none are yet practical.

To realize a useful quantum computer, Google, IBM, Microsoft, Amazon, and others are pouring resources into machines that run on a menagerie of qubits. The most popular approach, favored by Google and IBM, involves tiny loops of superconducting wire. Honeywell and IonQ are pursuing atomic qubits made of trapped ions. Researchers in China are building intricate, Rube-Goldberg-like machines on lab benches to run quantum computations with mirrors and light.

The quantum race is anything but settled, and as outlined in a paper published this week in Nature, there’s a new horse on the track. Instead of superconducting loops, ions, or photons, a team of scientists led by the Department of Energy’s Argonne National Laboratory, made qubits from single electrons.

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When the Hunga Tonga-Hunga Ha’apai volcano erupted on Jan. 15, 2022, it sent atmospheric shock waves, sonic booms, and tsunami waves around the world. Now, scientists are finding the volcano’s effects also reached space.

Analyzing data from NASA’s Ionospheric Connection Explorer (ICON) mission and ESA’s (the European Space Agency) Swarm satellites, scientists found that in the hours after the eruption, hurricane-speed winds and unusual electric currents formed in the —Earth’s electrified upper atmospheric layer at the edge of .

“The volcano created one of the largest disturbances in space we’ve seen in the modern era,” said Brian Harding, a physicist at University of California, Berkeley, and lead author on a new paper discussing the findings. “It is allowing us to test the poorly understood connection between the lower atmosphere and space.”

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Recent technological advances have enabled the creation of increasingly sophisticated sensors that can track movements and changes in real-world environments with remarkable levels of precision. Many engineers are now working to make these sensors thinner so that they can be embedded in a variety of devices, including robotic limbs and wearable devices.

Researchers at Hong Kong University of Science and Technology have recently developed a thin sensor for computer vision applications, which is based on a micro lens array (MLA). MLAs are 1D or 2D arrays comprising several small lenses, which are generally arranged in either squared or hexagonal patterns.

“In this study, we combined an old technology, a micro array, with vision-based tactile ,” Xia Chen, one of the researchers who carried out the study, told TechXplore. “This work builds on the work using the pinhole arrays to capture the image. We wanted to achieve a thin-format vision-based tactile sensor, as few studies so far focused on changing the imaging system of vison-based .”

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Computational detective work by U.S. and German physicists has confirmed that cerium zirconium pyrochlore is a 3D quantum spin liquid.

Despite the name, quantum spin liquids are solid materials in which quantum entanglement and the geometric arrangement of atoms frustrate the natural tendency of electrons to magnetically order themselves in relation to one another. The in a quantum spin liquid is so severe that electrons fluctuate between quantum magnetic states no matter how cold they become.

Theoretical physicists routinely work with quantum mechanical models that manifest quantum spin liquids, but finding convincing evidence that they exist in actual physical materials has been a decades-long challenge. While a number of 2D or 3D materials have been proposed as possible quantum spin liquids, Rice University physicist Andriy Nevidomskyy has said there’s no established consensus among physicists that any of them qualify.

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Just as countries import a vast array of consumer goods across national borders, so living cells are engaged in a lively import-export business. Their ports of entry are sophisticated transport channels embedded in a cell’s protective membrane. Regulating what kinds of cargo can pass through the borderlands formed by the cell’s two-layer membrane is essential for proper functioning and survival.

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Nestled 30 feet underground in Menlo Park, California, a half-mile-long stretch of tunnel is now colder than most of the universe. It houses a new superconducting particle accelerator, part of an upgrade project to the Linac Coherent Light Source (LCLS) X-ray free-electron laser at the Department of Energy’s SLAC National Accelerator Laboratory.

Crews have successfully cooled the accelerator to minus 456 degrees Fahrenheit—or 2 Kelvin—a temperature at which it becomes superconducting and can boost electrons to high energies with nearly zero energy lost in the process. It is one of the last milestones before LCLS-II will produce X-ray pulses that are 10,000 times brighter, on average, than those of LCLS and that arrive up to a million times per second—a world record for today’s most powerful X-ray light sources.

“In just a few hours, LCLS-II will produce more X-ray pulses than the current laser has generated in its entire lifetime,” says Mike Dunne, director of LCLS. “Data that once might have taken months to collect could be produced in minutes. It will take X-ray science to the next level, paving the way for a whole new range of studies and advancing our ability to develop revolutionary technologies to address some of the most profound challenges facing our society.”

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When genes mutate, it can result in severe diseases of the human nervous system. Neuroscientists at Leipzig University and the University of Würzburg have now used fruit flies to demonstrate how, apart from the negative effect, the mutation of a neuronal gene can have a positive effect – namely higher IQ in humans. They have published their findings in the prestigious journal Brain.

Synapses are the contact points in the brain via which nerve cells ‘talk’ to one another. Disruptions in this communication lead to nervous system diseases, since altered synaptic proteins, for example, can impair this complex molecular mechanism. This can cause mild symptoms, but also very severe disabilities in those affected.

The interest of the two neurobiologists Professor Tobias Langenhan and Professor Manfred Heckmann, from Leipzig and Würzburg respectively, was aroused when they read in a scientific publication about a mutation that damages a synaptic protein. At first, the affected patients attracted scientists’ attention because the mutation caused them to go blind. However, doctors then noticed that the patients were also of above-average intelligence. “It’s very rare for a mutation to lead to improvement rather than loss of function,” says Langenhan, professor and holder of a chair at the Rudolf Schönheimer Institute of Biochemistry at the Faculty of Medicine.

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After months of shortages, pharmacies across the United States are being stocked with drugs to treat Covid-19. Now, the bottleneck has shifted to getting a prescription — and patients and public health agencies are looking to telehealth for help.

“Sometimes we hear telehealth is going to cure all of our challenges with access to health care, and that’s just not the case,” said Michelle Morse, chief medical officer of New York City’s department of health. “It’s a significant step forward in access, and yet there are still equity concerns with telehealth. It’s not a panacea.”

The patients most likely to know about and navigate digital health platforms to access the antivirals are typically younger, more affluent, and already well-served by the health system. And while a small group of public health departments are offering free telehealth, the end of the Health Resources and Services Administration Covid-19 Uninsured program means that uninsured patients may struggle to pay for teleservices, let alone any Covid care.

Michelle Lin, an emergency physician who works on an urgent care telehealth line in New York City, said many of the patients she sees turn to telehealth for Covid care have primary care doctors, but have struggled to get an appointment with them on short notice.

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