Israeli start-up MeMed aims to cut unnecessary prescribing of antibiotics with 15-minute procedure.
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PHILADELPHIA – Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls, according to new research published Thursday in Science from researchers in the Perelman School of Medicine at the University of Pennsylvania. Unexpectedly, the fat loss was not associated with decreased food intake or faster metabolism. Instead, the researchers discovered that TSLP stimulated the immune system to release lipids through the skin’s oil-producing sebaceous glands.
“This was a completely unforeseen finding, but we’ve demonstrated that fat loss can be achieved by secreting calories from the skin in the form of energy-rich sebum,” said principal investigator Taku Kambayashi, MD, PhD, an associate professor of Pathology and Laboratory Medicine at Penn, who led the study with fourth-year medical student Ruth Choa, PhD. “We believe that we are the first group to show a non-hormonal way to induce this process, highlighting an unexpected role for the body’s immune system.”
The animal model findings, Kambayashi said, support the possibility that increasing sebum production via the immune system could be a strategy for treating obesity in people.
NASA’s Space Launch System (SLS) rocket completed another milestone on its way to launch with the Umbilical Release and Retract Test (URRT). The URRT was performed on the rocket on September 19 while it stood in High Bay 3 of the Vehicle Assembly Building (VAB).
During the test, the swing arms and T0 umbilicals at the base of the rocket were commanded to retract from the vehicle as they will during a standard SLS launch countdown.
The test occurred on Mobile Launcher 1 (ML-1) and allowed ground teams to verify and validate the mechanisms, timings, and function of the umbilical release and retract system that will separate and move the arms — that support data and communications pathways as well as fueling ports for the upper stage — away from the SLS rocket and against the tower at launch.
DeepMind has given 3D structure to 350,000 proteins, including every one made by humans, promising a boon for medicine and drug design.
It’s easy for us, as the vast architectures of cells that we are, to take it for granted that multicellularity is an unqualified advantage. But as far as we can tell from fossils, life seems to have been cheerfully unicellular for its first billion years. And even today, there are far more unicellular organisms than multicellular ones on the planet.
Researchers have discovered that environments favoring clumpy growth are all that’s needed to quickly transform single-celled yeast into complex multicellular organisms.
The size of a grain of sand, dispersed microfliers could monitor air pollution, airborne disease, and environmental contamination.
Northwestern University engineers have added a new capability to electronic microchips: flight.
Microglia immune cells can join together to form networks when needed, a new study reports. However, certain mutations associated with Parkinson’s disease can impair this process.
NASA’s Hubble Space Telescope captured a cluster of distant galaxies surrounded in reflected light — an illusion first predicted by Einstein over a century ago.
They’re just the size of a grain of sand, but the microfliers can carry data-collecting sensors.
In a new study, a team of researchers proposed that Dark Matter detectors could also search for the elusive force that is causing our Universe to expand (Dark Energy)!
About 25 years ago, astrophysicists noticed something very interesting about the Universe. The fact that it was in a state of expansion had been known since the 1920s, thanks to the observation of Edwin Hubble. But thanks to the observations astronomers were making with the space observatory that bore his name (the Hubble Space Telescope), they began to notice how the rate of cosmic expansion was getting faster!
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