Lifeboat Foundation

Gene expression is inherently dynamic, due to complex regulation and stochastic biochemical events. Here the authors train a deep neural network to predict and dynamically control gene expression in thousands of individual bacteria in real-time which they then apply to control antibiotic resistance and study single-cell survival dynamics.

Nanotechnology has arrived in the turfgrass industry. What will the presence of tiny particles mean for fertility and plant protectant applications?

Immunizing enormous numbers of wild mice, however, is prohibitively difficult. By using genetic engineering, researchers could create white-footed mice that produced these antibodies from birth and could pass this ability on to their offspring. But did the island residents want to live with genetically engineered mice?

The answer was perhaps, but with caveats. In consulting with communities on this technology development, researchers found that community members preferred a cisgenic approach: They wanted white-footed mice that were engineered with DNA only from other white-footed mice.¹⁸ This would make the project more difficult for the researchers, and meant that a CRISPR-based gene drive, even one with limited spread, could not be used, since no white-footed mouse naturally has this gene-editing system. However, said Esvelt, “It’s their environment, so it’s their call.”

“We’re potentially causing an irreversible change to the environment,” said Telford. “We need to think about informed consent of the community as a proxy for informed consent of the environment. That’s been a real advance and something [that Esvelt] has pioneered—involving the communities from the very start.”

Find out more about the link between how oral bacteria can alter the balance between health and disease beyond the oral cavity.

‘Assembly theory’ aims to explain evolution without biology. Is it a dazzling breakthrough or an attempt to answer questions nobody asked?

Researchers at Massachusetts Institute of Technology (MIT) discovered that adding a highly conductive substance called carbon black to a water and cement mixture created a construction material that could also serve as a supercapacitor.

Supercapacitors can charge and discharge extremely efficiently but are typically not capable of storing energy for long amounts of time. So while they lack the functionality of traditional lithium-ion batteries – which are found in everything from smartphones to electric cars – they are a useful method of storing excess electricity generated from renewable energy sources like solar and wind.

Since first unveiling the technology last year, the team has now built a working proof-of-concept concrete battery, the BBC reported. The MIT researchers are now hoping to build a 45-cubic-metre (1,590-cubic-feet) version capable of meeting the energy needs of a residential home.

A team of roboticists at the University of Tokyo has taken a new approach to autonomous driving—instead of automating the entire car, simply put a robot in the driver’s seat. The group built a robot capable of driving a car and tested it on a real-world track. They also published a paper describing their efforts on the arXiv preprint server.

Recent years have seen increasing public attention and indeed concern regarding Unidentified Anomalous Phenomena (UAP). Hypotheses for such phenomena tend to fall into two classes: a conventional terrestrial explanation (e.g., human-made technology), or an extraterrestrial explanation (i.e., advanced civilizations from elsewhere in the cosmos). However, there is also a third minority class of hypothesis: an unconventional terrestrial explanation, outside the prevailing consensus view of the universe. This is the ultraterrestrial hypothesis, which includes as a subset the “cryptoterrestrial” hypothesis, namely the notion that UAP may reflect activities of intelligent beings concealed in stealth here on Earth (e.g., underground), and/or its near environs (e.g., the moon), and/or even “walking among us” (e.g., passing as humans). Although this idea is likely to be regarded sceptically by most scientists, such is the nature of some UAP that we argue this possibility should not be summarily dismissed, and instead deserves genuine consideration in a spirit of epistemic humility and openness.

WASHINGTON – Shipboard radar experts at RTX Corp. will build hardware for the new AN/SPY-6(V) Air and Missile Defense Radar (AMDR), which will be integrated into late-model Arleigh Burke-class (DDG 51) Aegis destroyer surface warships under terms of a $677.7 million U.S. Navy order announced Friday.

Officials of the Naval Sea Systems Command in Washington are asking the RTX Raytheon segment in Marlborough, Mass., for AN/SPY-6(V) shipboard radar hardware.

The Raytheon AN/SPY-6(V) AMDR will improve the Burke-class destroyer’s ability to detect hostile aircraft, surface ships, and ballistic missiles, Raytheon officials say. The AMDR will supersede the AN/SPY-1 radar, which has been standard equipment on Navy Aegis Burke-class destroyers and Ticonderoga-class cruisers.