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Controlling Sepsis, ARDS And Other Life Threatening Inflammatory Diseases — Prof. Dr. Niels Riedemann, MD, Ph.D. — CEO, InflaRx

Prof. Dr. Niels Riedemann, MD, Ph.D. is Chief Executive Officer and Founder of InflaRx (https://www.inflarx.de/Home/About-Inflarx/Team~Niels-C.-Riedemann~.h… a biopharmaceutical company focused on applying its proprietary anti-C5a and C5aR inhibitors to the treatment of life-threatening or debilitating inflammatory diseases with high unmet medical need.

Prof. Dr. Riedemann has over 15 years of experience in the biotech industry and drug development, as well as over 20 years of experience in complement immunology research. He founded InflaRx in 2007 and has served as Chief Executive Officer since inception of the company. He has been instrumental in and led numerous private and public financing rounds of the company and has been the responsible lead for its Nasdaq IPO in 2017. He is named inventor on several internationally granted core patents of InflaRx.

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A team led by researchers at UNC-Chapel Hill have made an extraordinary discovery that is reshaping our understanding of bubbles and their movement. Picture tiny air bubbles inside a container filled with liquid. When the container is shaken up and down, these bubbles engage in an unexpected, rhythmic “galloping” motion—bouncing like playful horses and moving horizontally, even though the shaking occurs vertically.

This counterintuitive phenomenon, revealed in a new study published in Nature, has significant implications for technology, from cleaning surfaces to improving in microchips and even advancing .

These galloping bubbles are already garnering significant attention: their impact in the field of fluid dynamics has been recognized with an award for their video entry at the most recent Gallery of Fluid Motion, organized by the American Physical Society.

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Dark matter is an elusive type of matter that does not emit, absorb or reflect light and is thus impossible to detect using conventional techniques employed in particle physics. In recent years, groups of physicists worldwide have been trying to observe this matter indirectly using advanced detectors and equipment, by detecting signals other than electromagnetic radiation that could be linked to its activity or interactions with other matter.

Researchers at Tokyo Metropolitan University, PhotoCross Co. Ltd, Kyoto Sangyo University and other collaborating institutions recently released the findings of the first search for dark matter that relied on data collected by WINERED, a near-infrared and high-dispersion spectrograph mounted on a in Chile.

Their paper, published in Physical Review Letters, sets the most stringent constraints to date on the lifetime of dark matter particles with masses between 1.8 and 2.7 eV.

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Researchers from the NIHR Moorfields Biomedical Research Centre and University College London have found that gene therapy improved visual acuity and preserved retinal structure in young children with AIPL1-associated severe retinal dystrophy. This is the first human trial of gene supplementation therapy targeting this condition.

Retinal dystrophy caused by biallelic variants in the AIPL1 gene leads to severe visual impairment from birth, with progressive degeneration and limited treatment options. Previous studies of early-onset rod-cone dystrophies, including AIPL1-related forms, highlighted a critical window for intervention during early childhood, when some photoreceptor structure remains intact. Prior research using Aipl1-deficient mouse models and human retinal organoids demonstrated partial restoration of photoreceptor function through .

In the study, “Gene therapy in children with AIPL1-associated severe retinal dystrophy: an open-label, first-in-human interventional study,” published in The Lancet, researchers administered a single subretinal injection of a recombinant adeno-associated (rAAV8.hRKp. AIPL1) carrying the AIPL1 gene to one eye of each child to assess the safety and efficacy of gene supplementation therapy in improving visual function and preserving retinal structure.

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The symptoms of schizophrenia vary greatly from person to person. A new study appearing in the American Journal of Psychiatry shows how these differences manifest themselves in the structure of the brain.

Schizophrenia is a complex mental health condition that affects perception, thought and emotions. This complexity is reflected in the individual manifestations of the disease: for some patients, perceptual disturbances are the main problem, while for others, cognitive impairments are more prevalent.

“In this sense, there is not one , but many, each with different neurobiological profiles,” says Wolfgang Omlor, first author of the study and senior physician at the University Hospital of Psychiatry Zurich.

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From integrated photonics to quantum information science, the ability to control light with electric fields—a phenomenon known as the electro-optic effect—supports vital applications such as light modulation and frequency transduction. These components rely on nonlinear optical materials, in which light waves can be manipulated by applying electric fields.

Conventional nonlinear optical materials such as lithium niobate have a large electro-optic response but are hard to integrate with silicon devices. In the search for silicon-compatible materials, aluminum scandium nitride (AlScN), which had already been flagged as an excellent piezoelectric—referring to a material’s ability to generate electricity when pressure is applied, or to deform when an electric field is applied—has come to the fore. However, better control of its properties and means to enhance its electro-optic coefficients are still required.

Researchers in Chris Van de Walle’s computational materials group at UC Santa Barbara have now uncovered ways to achieve these goals. Their study, published in Applied Physics Letters, explains how adjusting the material’s atomic structure and composition can boost its performance. Strong electro-optic response requires a large concentration of scandium—but the specific arrangement of the scandium atoms within the AlN crystal lattice matters.

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According to my recursive universe theory, we need Primordial Consciousness to explain the beginning of the first Universe. Please take a look at this YouTube video clip!

Consciousness is one of those topics that makes everyone uncomfortable—scientists, philosophers, and just about anyone who dares to question the nature of reality. Why? Because, despite all our technological advancements and scientific breakthroughs, we still don’t have a clear idea of what consciousness actually is or where it comes from. It’s the elephant in the room, the mystery that science can’t seem to crack. We can map the brain and understand its functions, but that still doesn’t explain why we experience thoughts, feelings, or self-awareness.

Some argue that consciousness is nothing more than the byproduct of biological processes, a lucky accident of evolution. But what if that’s not the whole story? What if consciousness isn’t a mere side effect of neurons firing but something far more fundamental—something that’s intertwined with the fabric of the universe itself?

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