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Serotonin functions as ‘prospective code for value’ in brain’s reward processing system

In our day-to-day lives, we’re constantly making a slew of decisions, from immediate matters to prospects on the far horizon. But the evolutionary nuts-and-bolts of how our brains weigh these numerous daily decisions and what role is played by the neurotransmitter serotonin has been shrouded in mystery.

Now, a new study led by an interdisciplinary University of Faculty of Medicine team delivers fascinating findings that potentially unravel a hidden aspect of what our nervous system’s extraordinarily complex serotonin system is really doing inside our skulls.

Published in the journal Nature, this study from a highly impactful international collaboration offers “broad implications across neuroscience, psychology, and psychiatry, enhancing our understanding of serotonin’s role in mood regulation, learning, and motivated behavior.”

The Particle That Might Explain Why Anything Exists at All

Scientists at CERN have made a groundbreaking discovery that deepens our understanding of why the Universe is made of matter and not antimatter. By analyzing an enormous trove of data from the LHC, researchers observed a subtle but significant asymmetry in the behavior of a particle called the be

The local microenvironment suppresses the synergy between irradiation and anti-PD1 therapy in breast-to-brain metastasis

Wischnewski et al. demonstrate suppressed CD8+ T cell cytotoxicity in breast cancer brain metastases, contrasting with genetically identical extracranial tumors. Neutrophils and Trem2+ macrophages drive this suppression, limiting the efficacy of combined irradiation and anti-PD1 therapy, highlighting potential therapeutic targets for brain metastases.

Earth’s First Crust Was Continental — Long Before Plate Tectonics Began

New research suggests that Earth’s first crust, formed over 4.5 billion years ago, already carried the chemical traits we associate with modern continents. This means the telltale fingerprints of continental crust didn’t need plate tectonics to form, turning a long-standing theory on its head.

Using simulations of early Earth conditions, scientists found that the intense heat and molten environment of the planet’s infancy created these signatures naturally. The finding shakes up how we understand Earth’s evolution and could even influence how we think about crust formation on other planets.

A surprising shift in earth’s history.

Cracking the Devil’s Staircase: How a Time Crystal Danced Through Chaos

A team of physicists has made groundbreaking observations in a semiconductor-based time crystal by periodically driving it with light. As the frequency was altered, the system transitioned from perfect synchronization to complex chaos, forming structures known as the Farey tree and the devil’s st

Korean Scientists Develop World’s Most Efficient Hydrogen Catalyst Using 1/3 the Precious Metal

Designed a “core-shell structure catalyst” using cost-effective ruthenium to improve its potential for commercialization. Selected as a cover paper in the prestigious catalysis journal Energy & Environmental Science. Seoul National University’s College of Engineering has announced a significa