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Researchers at Washington University School of Medicine in St. Louis have found a new druggable pathway that potentially could be used to help prevent Alzheimer’s dementia.

Amyloid beta accumulation in the brain is the first step in the development of Alzheimer’s dementia. Scientists have poured countless hours and millions of dollars into finding ways to clear amyloid away before cognitive symptoms arise, with largely disappointing results.

In this study, published Aug. 24 in the journal Brain, researchers found a way to increase clearance of waste products from the brains of mice by ramping up a genetic quirk known as readthrough. This same strategy also may be effective for other characterized by the buildup of toxic proteins, such as Parkinson’s disease, the researchers said.

Since we began space exploration in the mid-20th century, space agencies have relied on sending humans and robots into space. But should we leave space exploration entirely to robots?

Or should we consider sending humans to explore a new space world instead of robots? You are about to find satisfying answers to these curious questions.

Unlike traveling from one destination to another on Earth, exploring space comes with greater responsibilities. Space agencies hoping to explore a new space world must make a lot of planning to guarantee their success.

“Robo Sapien” taken from the album “The Machinists Of Joy”.
Directed by: Jay Gillian.
Camera OP and Computer Animation: Shane Williams.
Produced by Cinematek Film & Television.
Robo Sapien provided by: JG and the Robots www.JGandtheRobots.com.

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Bishop: They can still be computationally very expensive. Additionally, emulators learn from data, so they’re typically not more accurate than the data used to train them. Moreover, they may give insufficiently accurate results when presented with scenarios that are markedly different from those on which they’re trained.

“I believe in “use-inspired basic research”—[like] the work of Pasteur. He was a consultant for the brewing industry. Why did this beer keep going sour? He basically founded the whole field of microbiology.” —Chris Bishop, Microsoft Research.