Lifeboat Foundation

BepiColombo’s second Mercury flyby on June 23 takes the probe one step closer to orbiting the closest planet to the Sun.

PHILADELPHIA — In the summer of 2010, Bill Ludwig and Doug Olson were battling an insidious blood cancer called chronic lymphocytic leukemia (CLL). They’d both received numerous treatments, and as remaining options became scarce, they volunteered to become the first participants in a clinical trial of an experimental therapy underway at the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania. The treatment would eradicate their end-stage leukemia, generate headlines across the globe, and usher in a new era of highly personalized medicine. Called Chimeric Antigen Receptor (CAR) T cells, these genetically modified tumor-targeting cells are a living drug made for each patient out of their own cells. Today, an analysis of these two patients published in Nature from the Penn researchers and colleagues from Children’s Hospital of Philadelphia explains the longest persistence of CAR T cell therapy recorded to date against CLL, and shows that the CAR T cells remained detectable at least a decade after infusion, with sustained remission in both patients.

“This long-term remission is remarkable, and witnessing patients living cancer-free is a testament to the tremendous potency of this “living drug” that works effectively against cancer cells,” said first author J. Joseph Melenhorst, PhD, a research professor of Pathology and Laboratory Medicine at Penn. “Witnessing our patients respond well to this innovative cellular therapy makes all of our efforts so worthwhile. being able to give them more time to live and to spend it with loved ones.”

CLL, the first cancer in which CAR T cells were studied and used at Penn, is the most common type of leukemia in adults. While treatment of the disease has improved, it remains incurable with standard approaches. Eventually, patients can become resistant to most therapies, and many still die of their disease.

UPI, an cheap(currently free), proven, alternative payments system designed to be secure, reliable, and interoperable among different payment companies, encouraging a innovative ecosystem.

India’s UPI payment platform is delivering on financial inclusion in ways that Bitcoin and blockchain have yet to do.

Fossils from a South African cave are 3.4 to 3.6m years old and walked the Earth at same time as east African relatives.

Good news for NASA’s Lucy spacecraft, the solar array of which is now almost completely deployed.

Using the Victor M. Blanco Telescope, Donatiello captured minute glimpses of the galaxy in Chile, particularly at the Cerro Tololo Inter-American Observatory.

At the time, David Martinez-Delgado, another astronomer from Spain’s Instituto de Astrofisica de Andalucia, was conducting separate research regarding the lingering galaxies around Andromeda.

Upon learning the existence of the fossil galaxy, the scientists propose an argument that this could be a speck of an ancient galaxy. Its stars are said to be a former part of it.

We know the brain changes after traumatic injury, and now we have maps from mice showing what that change looks like.

A team of scientists has traced connections between nerve cells throughout the entire brain of mice, showing that distant parts of the brain become disconnected after a head injury.

The stunning visualizations of brain-wide connectivity could help scientists understand how a traumatic brain injury, or TBI, alters cross-talk between different cells and brain regions, first in mice and then in humans.

Lex Friedman interviews Google’s Deep Mind founder and CEO Demis Hassabis. In this clip Lex Friedman asks about the claim that LaMDA is sentient.

Lex Fridman Podcast full episode: https://www.youtube.com/watch?v=Gfr50f6ZBvo.
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Continue reading “Lex Fridman on Google engineer’s claim that AI became sentient” »

A new study from the University of Cambridge reveals that electrons can simultaneously possess different energy levels.

Electrons, one of the most fundamental components of our universe, still hold a few secrets that puzzle modern scientists. Since the 1920s, physicists have worked to try and unravel the workings of these negatively charged particles, and how they behave in different situations. Now, research conducted at the University of Cambridge has shed new light on a pair of key factors–the spins and charges of electrons–revealing even more about their unique behavior.

Background: Spin and Charge

Continue reading “Mind-Bending Physics Reveals Electrons Travel in ‘Lanes’ While Moving Along Quantum Wires” »