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Researchers at Washington University School of Medicine in St. Louis have found a new druggable pathway that potentially could be used to help prevent Alzheimer’s dementia.

Amyloid beta accumulation in the brain is the first step in the development of Alzheimer’s dementia. Scientists have poured countless hours and millions of dollars into finding ways to clear amyloid away before cognitive symptoms arise, with largely disappointing results.

In this study, published Aug. 24 in the journal Brain, researchers found a way to increase clearance of waste products from the brains of mice by ramping up a genetic quirk known as readthrough. This same strategy also may be effective for other characterized by the buildup of toxic proteins, such as Parkinson’s disease, the researchers said.

Since we began space exploration in the mid-20th century, space agencies have relied on sending humans and robots into space. But should we leave space exploration entirely to robots?

Or should we consider sending humans to explore a new space world instead of robots? You are about to find satisfying answers to these curious questions.

Unlike traveling from one destination to another on Earth, exploring space comes with greater responsibilities. Space agencies hoping to explore a new space world must make a lot of planning to guarantee their success.

“Robo Sapien” taken from the album “The Machinists Of Joy”.
Directed by: Jay Gillian.
Camera OP and Computer Animation: Shane Williams.
Produced by Cinematek Film & Television.
Robo Sapien provided by: JG and the Robots www.JGandtheRobots.com.

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Bishop: They can still be computationally very expensive. Additionally, emulators learn from data, so they’re typically not more accurate than the data used to train them. Moreover, they may give insufficiently accurate results when presented with scenarios that are markedly different from those on which they’re trained.

“I believe in “use-inspired basic research”—[like] the work of Pasteur. He was a consultant for the brewing industry. Why did this beer keep going sour? He basically founded the whole field of microbiology.” —Chris Bishop, Microsoft Research.

Life science continued dominating the research schedule aboard the International Space Station on Wednesday to benefit humans living on and off the Earth. The seven Expedition 67 orbital residents explored how living in microgravity affects tissue regeneration, crew psychology, and the human digestion system.

Learning to heal wounds in space is critical as NASA and its international partners plan crewed missions to the Moon, Mars, and beyond. Four station astronauts have been partnering together this week for the skin healing study taking place inside the Kibo laboratory module. Flight Engineers Kjell Lindgren, Bob Hines, and Jessica Watkins, all from NASA, with Samantha Cristoforetti of ESA (European Space Agency), are studying surgical techniques such as biopsies, suture splints, and wound dressing, inside Kibo’s Life Science Glovebox.

Scientists on Earth seek to identify the molecular mechanisms that occur during tissue regeneration in weightlessness. Observations may offer advanced therapies and provide insights into how space-caused accelerated skin aging affects an astronaut’s healing properties. The biomedical experiment may also contribute to better wound healing techniques on Earth.

Circa 2014 face_with_colon_three


Electronic transistors, which act as miniature switches for controlling the flow of electrical current, underpin modern-day microelectronics and computers. State-of-the-art microprocessor chips contain several billion transistors that switch signals flowing in electrical wires and interconnects. With increasing data-processing speeds and shrinking chip sizes, however, wires and interconnects waste considerable energy as heat.

One alternative is to replace electrical interconnects with energy-efficient that carry data using . However, a practical analogue of the transistor for optical interconnects does not yet exist. Hence, Vivek Krishnamurthy from the A*STAR Data Storage Institute and co-workers in Singapore and the United States are developing a practical ‘photonic transistor’ for optical interconnects that can control light signals in a similar manner to electronic .

The researchers’ latest photonic transistor design is based on prevalent semiconductor technology and offers attractive attributes of high switching gain, low switching power and high operating speed.