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The Nobel Prize in Physics was awarded to Alain Aspect, John F. Clauser and Anton Zeilinger on Tuesday for work that has “laid the foundation for a new era of quantum technology,” the Nobel Committee for Physics said.

The scientists have each conducted “groundbreaking experiments using entangled quantum states, where two particles behave like a single unit even when they are separated,” the committee said in a briefing. Their results, it said, cleared the way for “new technology based upon quantum information.”

The laureates’ research builds on the work of John Stewart Bell, a physicist who strove to address the question of whether particles, having flown too far apart for there to be normal communication between them, can still function in concert.

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Were you unable to attend Transform 2022? Check out all of the summit sessions in our on-demand library now! Watch here.

The open-source Linux operating system is an essential component of the cloud and enterprise application delivery. In fact, every cloud service, even Microsoft, offers Linux-based compute resources and Linux is often the default choice for embedded and internet of things (IoT) devices. Among the major Linux distribution vendors today are IBM’s Red Hat business unit, German vendor SUSE and Canonical, which develops the Ubuntu Linux distribution.

The market for Linux is forecast to grow to $22.15 billion by 2029, according to Fortune Business Insights, up from $6.27 billion in 2022.

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It is a commonly accepted view that light stimulation of mammalian photoreceptors causes a graded change in membrane potential instead of developing a spike. The presynaptic Ca2+ channels serve as a crucial link for the coding of membrane potential variations into neurotransmitter release. Cav1.4 L-type Ca2+ channels are expressed in photoreceptor terminals, but the complete pool of Ca2+ channels in cone photoreceptors appears to be more diverse. Here, we discovered, employing whole-cell patch-clamp recording from cone photoreceptor terminals in both sexes of mice, that their Ca2+ currents are composed of low-(T-type Ca2+ channels) and high-(L-type Ca2+ channels) voltage-activated components. Furthermore, Ca2+ channels exerted self-generated spike behavior in dark membrane potentials, and spikes were generated in response to light/dark transition. The application of fast and slow Ca2+ chelators revealed that T-type Ca2+ channels are located close to the release machinery. Furthermore, capacitance measurements indicated that they are involved in evoked vesicle release. Additionally, RT-PCR experiments showed the presence of Cav3.2 T-type Ca2+ channels in cone photoreceptors but not in rod photoreceptors. Altogether, we found several crucial functions of T-type Ca2+ channels, which increase the functional repertoire of cone photoreceptors. Namely, they extend cone photoreceptor light-responsive membrane potential range, amplify dark responses, generate spikes, increase intracellular Ca2+ levels, and boost synaptic transmission.

SIGNIFICANCE STATEMENT Photoreceptors provide the first synapse for coding light information. The key elements in synaptic transmission are the voltage-sensitive Ca2+ channels. Here, we provide evidence that mouse cone photoreceptors express low-voltage-activated Cav3.2 T-type Ca2+ channels in addition to high-voltage-activated L-type Ca2+ channels. The presence of T-type Ca2+ channels in cone photoreceptors appears to extend their light-responsive membrane potential range, amplify dark response, generate spikes, increase intracellular Ca2+ levels, and boost synaptic transmission. By these functions, Cav3.2 T-type Ca2+ channels increase the functional repertoire of cone photoreceptors.

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Scientists trained a machine learning tool to capture the physics of electrons moving on a lattice using far fewer equations than would typically be required, all without sacrificing accuracy. A daunting quantum problem that until now required 100,000 equations has been compressed into a bite-size task of as few as four equations by physicists using artificial intelligence. All of this was accomplished without sacrificing accuracy. The work could revolutionize how scientists investigate systems containing many interacting electrons. Furthermore, if scalable to other problems, the approach could potentially aid in the design of materials with extremely valuable properties such as superconductivity or utility for clean energy generation.

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SEOUL, South Korea — North Korea on Tuesday fired an intermediate-range ballistic missile over Japan, its neighbors said, escalating tests of weapons designed to strike key targets in regional U.S. allies.

It is the most significant missile test by North Korea since January, when it fired the Hwasong-12 intermediate-range missile capable of reaching the U.S. territory of Guam. It is also the first time that a North Korean missile has flown over Japan since 2017.

The Japanese prime minister’s office said at least one missile fired from North Korea flew over Japan and was believed to have landed in the Pacific Ocean.

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Researchers at Google Deepmind and the University of Oxford have concluded that it’s now “likely” that superintelligent AI will spell the end of humanity — a grim scenario that more and more researchers are starting to predict.

In a recent paper published in the journal AI Magazine, the team — comprised of DeepMind senior scientist Marcus Hutter and Oxford researchers Michael Cohen and Michael Osborne — argues that machines will eventually become incentivized to break the rules their creators set to compete for limited resources or energy.

“Under the conditions we have identified, our conclusion is much stronger than that of any previous publication — an existential catastrophe is not just possible, but likely,” Cohen, Oxford University engineering student and co-author of the paper, tweeted earlier this month.

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Scientists have discovered a fluorescent protein that flouts trade-off relationships.

Scientific research institute RIKEN produced bright and photostable green fluorescent protein from Japanese jellyfish. Published in Nature Biotechnology.

Proteins that emit green light when illuminated are effective instruments for capturing images of intricate cell architecture. Such fluorescent proteins can be attached to target structures of interest, which light up when exposed to blue light.

Kuroshio Biological Research Foundation.

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