Wang Wei and Deng Ziqing, the co-corresponding authors, determined that a shortage of this retinoic acid prevented mice from regenerating their ear pinna (the outer ear).
Researchers have demonstrated that a genetic switch for organ regeneration exists, after restoring damaged outer ears in mice.
This has ignited hope that similar switches might exist for other organs, even in humans.
The study conducted by the National Institute of Biological Sciences, Beijing, zeroes in on a crucial molecule: retinoic acid, a derivative of vitamin A.