Menopause reshapes the brain in surprising ways — but it may also reveal the brain’s remarkable ability to adapt.
During menopause, many women notice episodes of “brain fog,” which can include forgetfulness, difficulty focusing, and persistent mental tiredness. These challenges are often linked to shifting hormone levels. To better understand what is happening in the brain during this life stage, researchers reviewed previously published studies examining how structural brain changes relate to cognitive, emotional, and physical health outcomes. Their findings were presented at the 2025 Annual Meeting of The Menopause Society.
Structural Brain Changes During Menopause.









