Toggle light / dark theme

Get the latest international news and world events from around the world.

Log in for authorized contributors

Role of PARP in TNBC: Mechanism of Inhibition, Clinical Applications, and Resistance

Triple-negative breast cancer is a combative cancer type with a highly inflated histological grade that leads to poor theragnostic value. Gene, protein, and receptor-specific targets have shown effective clinical outcomes in patients with TNBC. Cells are frequently exposed to DNA-damaging agents. DNA damage is repaired by multiple pathways; accumulations of mutations occur due to damage to one or more pathways and lead to alterations in normal cellular mechanisms, which lead to development of tumors. Advances in target-specific cancer therapies have shown significant momentum; most treatment options cause off-target toxicity and side effects on healthy tissues.

Jermonica Boardley & Joseph Scrocco — Novel Harm Reduction Strategies For The Opioid Epidemic

Novel Harm Reduction Strategies For The Opioid Epidemic — Harmguard FX — Jermonica Boardley & Joseph Scrocco — Sivad Group LLC / Diagnostic Solutions Group


Jermonica Boardley is President and CEO of SIVAD Diagnostic Medical Group LLC (https://sivadppe.com/), a minority-owned company dedicated to addressing the unique needs of underserved and unserved communities in the United States and globally, which most recently announced the launch of HarmGuard FX (https://www.harmstopper.com/), a single, low-cost strip that provides an affordable, reliable way for people to test substances for fentanyl and xylazine (popularly known as tranq), two dangerous adulterants that are exacerbating the already critical opioid epidemic.

Ms. Boardley is a graduate of Delaware State University, brings over 20 years of diverse corporate leadership experience to her role as President and CEO and her expertise spans Accounting, Finance, Human Resources, Communications, and Diversity, Equity & Inclusion (DE&I).

Joseph Scrocco, is President & CEO, Diagnostic Solutions Group (https://www.diagnosticsolutionsgroup.com/), the developer of HarmGuardFX, and their company has developed custom diagnostic solutions for over 25 years ranging from complex mass screening for blood banks to individual point-of-care testing with a focus on large-scale, global diagnostic needs, including antibody, molecular, and antigen tests in traditional and non-traditional settings. Their clients include Johnson & Johnson; Pfizer; Novo Nordisk; Abbott Labs; Ortho Clinical Diagnostics; the Red Cross; the governments of Nigeria, Ivory Coast, Bangladesh, Liberia, Jamaica, India, Mali; numerous Broadway companies; plus, hundreds of hospitals, urgent care centers, and long-term care facilities.

Mr. Scrocco has a MS in Neurophysiology from University of Medicine and Dentistry of New Jersey, and an MA in Information Systems from New York University.

Liz Scott, Co-Executive Director, Alex’s Lemonade Stand Foundation for Childhood Cancer

Alex’s lemonade stand foundation — fighting childhood cancer, one cup at a time! liz scott, co-executive director, alex’s lemonade stand foundation.


Liz Scott is Co-Executive Director, of Alex’s Lemonade Stand Foundation for Childhood Cancer (ALSF — https://www.alexslemonade.org/), an organization which emerged from the front yard lemonade stand of her daughter, Alexandra “Alex” Scott (1996−2004).

In 2000, at the age of four, Alex announced that she wanted to hold a lemonade stand to raise money to help find a cure for other children with cancer, herself already bravely fighting neuroblastoma, which she was diagnosed with at age one.

Over her lifetime, Alex would raise over $1 million before she passed away in 2004 at the age of 8. Since then, Liz and her husband Jay have worked alongside thousands of supporters across the country to carry on Alex’s legacy of hope.

To date, ALSF has raised more than $250 Million toward fulfilling Alex’s dream of finding a cure, funding over 1,000 pediatric cancer research projects nationally.

How a 5-minute phone call between a millennial billionaire and an economist created a $50 million grant program backed by Musk, Thiel, Zuckerberg and more tech luminaries

In March 2020, an experiment in science philanthropy was hatched in the span of a five-minute call.

Patrick Collison, the now 34-year-old billionaire CEO of the online payments company Stripe, and economist Tyler Cowen were chewing over a shared concern: Scientific progress seemed to be slowing down. As the first pandemic lockdowns went into effect, researchers were in a holding pattern, waiting to hear if they could redirect their federal grants to COVID-related work. Collison and Cowen worried that the National Institutes of Health wasn’t moving quickly enough, so they launched Fast Grants to get emergency research dollars to virologists, coronavirus experts, and other scientists rapidly.

“We thought: Let’s just do this,” Cowen recalls. “It was a bit like put up or shut up.”

Elon Musk Says Universe May Be Twice as Old as We Think, Dark Matter Seems “Sketch”

Elon Musk, the omnipotent ruler of the Twitterverse, has chimed in and has decreed that the actual physical universe is “possibly” twice as old as we think it is.

Make of that what you will.

Musk was responding to noted misinformation peddler and comedian Joe Rogan, who linked to a press release about a controversial new paper that indeed suggests the universe could be 26.7 billion years old, almost twice as the general consensus among scientists.

Elon Musk confirms Tesla is in ‘early’ talk to license self-driving tech to ‘major’ automaker

Elon Musk confirmed that Tesla is currently in ‘early’ discussions to license its self-driving technology with a ‘major’ automaker.

At the end of his opening remarks for Tesla’s Q2 2022 earnings call following the release of the automaker’s financial results, CEO Elon Musk said that he wanted to “strongly emphasize” that Tesla is open to licensing its self-driving technology to other automakers.

That’s something that the CEO has been frequently mentioning as of late.

James Cameron Doubts AI Can Write Good Scripts, Says the ‘Weaponization of AI Is the Biggest Danger’: ‘I Warned You in 1984 and You Didn’t Listen’

James Cameron has no intention of using artificial intelligence to write a film script. In a new interview with CTV News, the Oscar winner expressed doubt over AI bots being able to write “a good story.”

According to Cameron: “I just don’t personally believe that a disembodied mind that’s just regurgitating what other embodied minds have said — about the life that they’ve had, about love, about lying, about fear, about mortality — and just put it all together into a word salad and then regurgitate it…I don’t believe that’s ever going to have something that’s going to move an audience. You have to be human to write that. I don’t know anyone that’s even thinking about having AI write a screenplay.”

5 Healthy Habits That Help You During Lung Cancer Treatment

If you’re fighting cancer, a healthy lifestyle can help you stay well during and after treatment. Research suggests that good nutrition, exercise and other healthy behaviors may improve your quality of life during treatment.

“Taking charge of your health by developing healthy habits empowers you to cope better with your treatment and any side effects you may have,” says Lonny Yarmus, D.O., a board certified interventional pulmonologist at the Lung Cancer Program at the Sidney Kimmel Comprehensive Cancer Center.